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Tdark
SPATA5L1
Spermatogenesis-associated protein 5-like protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000305560
  • ENSP00000305494
  • ENSG00000171763
  • ENST00000531970
  • ENSP00000436823
  • ENST00000638607
  • ENSP00000492775
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.9
molecular function
0.73
gene perturbation
0.71
histone modification site profile
0.66
transcription factor binding site profile
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.56   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 94   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.56   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 94   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (96)
CINP
Tbio
Family:  Enzyme
Novelty:  0.07004715
p_int:  1
Score:  0.825
Data Source:  BioPlex,STRINGDB
HSPA1A
Tchem
Novelty:  0.00069195
p_int:  0.999999999
Score:  0.303
Data Source:  BioPlex,STRINGDB
RIPK4
Tchem
Family:  Kinase
Novelty:  0.00818379
p_int:  0.999988651
p_ni:  0.000011335
p_wrong:  1.4e-8
Score:  0.292
Data Source:  BioPlex,STRINGDB
C1orf109
Tdark
Novelty:  0.93042195
p_int:  0.998423756
p_ni:  0.000004463
p_wrong:  0.001571781
Score:  0.874
Data Source:  BioPlex,STRINGDB
FMN2
Tbio
Novelty:  0.02031944
p_int:  0.997765327
p_ni:  0.00220728
p_wrong:  0.000027393
Score:  0.291
Data Source:  BioPlex,STRINGDB
CAPN2
Tchem
Novelty:  0.00431673
p_int:  0.997454542
p_ni:  0.002545458
Data Source:  BioPlex
TIMM8A
Tbio
Family:  Enzyme
Novelty:  0.00954602
p_int:  0.980195947
p_ni:  0.019804053
Data Source:  BioPlex
SPATA5
Tbio
Family:  Enzyme
Novelty:  0.00416454
p_int:  0.960805932
p_ni:  0.039194068
Score:  0.868
Data Source:  BioPlex,STRINGDB
FAS
Tbio
Novelty:  0.00043286
p_int:  0.958368691
p_ni:  0.041631309
Data Source:  BioPlex
MRPL4
Tdark
Novelty:  0.27290276
p_int:  0.945561446
p_ni:  0.054438554
Score:  0.153
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
9
8
10
15.9
99.6
creatinine measurement
5
5
7
96.6
urinary albumin to creatinine ratio
3
3
3
79.3
1
1
0
1.1
66.8
urinary potassium to creatinine ratio
1
1
1
59.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
10
15.9
99.6
creatinine measurement
7
96.6
urinary albumin to creatinine ratio
3
79.3
0
1.1
66.8
urinary potassium to creatinine ratio
1
59.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
spermatogenesis associated 5 like 1
VGNC:6589
743404
Macaque
spermatogenesis associated 5 like 1 [Source:HGNC Symbol;Acc:HGNC:28762]
Rat
RGD:1595990
691729
Dog
spermatogenesis associated 5 like 1
VGNC:46716
609256
Cow
spermatogenesis associated 5 like 1
VGNC:35188
533070
Species
Name
OMA
EggNOG
Inparanoid
Chimp
spermatogenesis associated 5 like 1
Macaque
spermatogenesis associated 5 like 1 [Source:HGNC Symbol;Acc:HGNC:28762]
Rat
Dog
spermatogenesis associated 5 like 1
Cow
spermatogenesis associated 5 like 1
Publication Statistics
PubMed Score 2.56
PubMed score by year
PubTator Score 0.75
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title