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Tdark
SPATA46
Spermatogenesis-associated protein 46

Protein Summary
Description
Play a role in spermiogenesis and fertilization.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367935
  • ENSP00000356912
  • ENSG00000171722

Symbol
  • C1orf111
  • HSD20
  • C1orf111
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.93   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 132   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.93   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 132   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (21)
SNX24
Tdark
Novelty:  0.20838126
p_int:  0.999998583
p_ni:  0.000001416
p_wrong:  1e-9
Score:  0.686
Data Source:  BioPlex,STRINGDB
MDM4
Tchem
Novelty:  0.00321558
p_int:  0.999970569
p_ni:  0.000029369
p_wrong:  6.3e-8
Score:  0.798
Data Source:  BioPlex,STRINGDB
GAPVD1
Tbio
Family:  Enzyme
Novelty:  0.13142098
p_int:  0.999945558
p_ni:  0.000054442
Score:  0.823
Data Source:  BioPlex,STRINGDB
CSNK1A1
Tchem
Family:  Kinase
Novelty:  0.00636472
p_int:  0.999930053
p_ni:  0.000069946
Score:  0.821
Data Source:  BioPlex,STRINGDB
TYW5
Tbio
Novelty:  0.1382439
p_int:  0.999778426
p_ni:  0.000221573
Score:  0.243
Data Source:  BioPlex,STRINGDB
MGLL
Tchem
Family:  Enzyme
Novelty:  0.00196912
p_int:  0.999239975
p_ni:  0.000752525
p_wrong:  0.0000075
Score:  0.29
Data Source:  BioPlex,STRINGDB
HLCS
Tchem
Family:  Enzyme
Novelty:  0.01597449
p_int:  0.985988398
p_ni:  0.014002949
p_wrong:  0.000008653
Score:  0.513
Data Source:  BioPlex,STRINGDB
PRSS54
Tdark
Family:  Enzyme
Novelty:  0.4382869
Score:  0.67
Data Source:  STRINGDB
PCDHA2
Tdark
Novelty:  1.54807804
Score:  0.67
Data Source:  STRINGDB
HEPHL1
Tbio
Novelty:  0.44678065
Score:  0.63
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
longitudinal BMI measurement
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
longitudinal BMI measurement
1
21.5
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
spermatogenesis associated 46
VGNC:4980
747696
Macaque
spermatogenesis associated 46
720087
Mouse
MGI:1924175
76925
Rat
RGD:1565283
498274
Dog
spermatogenesis associated 46
VGNC:46715
100686306
Species
Name
OMA
EggNOG
Inparanoid
Chimp
spermatogenesis associated 46
Macaque
spermatogenesis associated 46
Mouse
Rat
Dog
spermatogenesis associated 46
Publication Statistics
PubMed Score 2.93
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title