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Tbio
SPATA25
Spermatogenesis-associated protein 25

Protein Summary
Description
May play a role in spermatogenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372519
  • ENSP00000361597
  • ENSG00000149634

Symbol
  • C20orf165
  • TSG23
  • TSG23
  • C20orf165
  • dJ337O18.8
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.85
cell type or tissue
0.69
tissue sample
0.62
cell line
0.46
chemical
0.41


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.13   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 56   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.13   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 56   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
TAF3
Tbio
Family:  Epigenetic
Novelty:  0.05517331
p_int:  0.999999996
p_ni:  4e-9
Data Source:  BioPlex
TAF13
Tbio
Novelty:  0.08566117
p_int:  0.999999995
p_ni:  4e-9
p_wrong:  1e-9
Data Source:  BioPlex
TAF1
Tchem
Family:  Kinase
Novelty:  0.00555929
p_int:  0.999999994
p_ni:  6e-9
Data Source:  BioPlex
TAF11
Tchem
Novelty:  0.10299251
p_int:  0.999999992
p_ni:  8e-9
Data Source:  BioPlex
TAF2
Tbio
Novelty:  0.0397428
p_int:  0.999999946
p_ni:  5.4e-8
Data Source:  BioPlex
TAF7
Tbio
Novelty:  0.05316615
p_int:  0.999999923
p_ni:  7.7e-8
Data Source:  BioPlex
TAF9B
Tbio
Novelty:  0.0285313
p_int:  0.999999844
p_ni:  1.56e-7
Data Source:  BioPlex
TAF4B
Tbio
Novelty:  0.70515005
p_int:  0.999999658
p_ni:  3.1e-7
p_wrong:  3.3e-8
Data Source:  BioPlex
TAF5
Tbio
Novelty:  0.05443551
p_int:  0.99999932
p_ni:  6.8e-7
Data Source:  BioPlex
TAF6
Tbio
Novelty:  0.04357176
p_int:  0.99999888
p_ni:  7.62e-7
p_wrong:  3.58e-7
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (34)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
15
15
26
99.7
triglyceride measurement
14
12
24
3.3
99.4
sleep duration
4
3
4
90.1
apolipoprotein B measurement
2
2
2
86.8
lipoprotein measurement
1
2
2
86
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
26
99.7
triglyceride measurement
24
3.3
99.4
sleep duration
4
90.1
apolipoprotein B measurement
2
86.8
lipoprotein measurement
2
86
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
spermatogenesis associated 25
VGNC:6272
742146
Macaque
spermatogenesis associated 25
709097
Mouse
MGI:1922892
75642
Rat
RGD:1564523
499943
Dog
spermatogenesis associated 25
VGNC:54734
100683792
Species
Name
OMA
EggNOG
Inparanoid
Chimp
spermatogenesis associated 25
Macaque
spermatogenesis associated 25
Mouse
Rat
Dog
spermatogenesis associated 25
Publication Statistics
PubMed Score 1.13
PubMed score by year
PubTator Score 0.50
PubTator score by year
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Related Publications
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PMID
Year
Title