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Tbio
SPATA19
Spermatogenesis-associated protein 19, mitochondrial

Protein Summary
Description
May have a role in spermiogenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000299140
  • ENSP00000299140
  • ENSG00000166118
  • ENST00000532889
  • ENSP00000435248

Symbol
  • SPERGEN1
  • CT132
  • SPAS1
  • spergen1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.83
cell type or tissue
0.65
cellular component
0.5
cell line
0.49
transcription factor
0.4


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.66   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 106   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.66   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (39)
RHEB
Tbio
Family:  Enzyme
Novelty:  0.00313935
p_int:  0.99955999
p_ni:  0.000440008
p_wrong:  2e-9
Score:  0.188
Data Source:  BioPlex,STRINGDB
MFF
Tbio
Novelty:  0.00411615
p_int:  0.998080911
p_ni:  0.000010736
p_wrong:  0.001908352
Score:  0.305
Data Source:  BioPlex,STRINGDB
MTHFR
Tbio
Family:  Enzyme
Novelty:  0.00018162
p_int:  0.927669707
p_ni:  0.072330293
Score:  0.189
Data Source:  BioPlex,STRINGDB
RSPRY1
Tdark
Novelty:  0.26883105
p_int:  0.893513687
p_ni:  0.106486311
p_wrong:  3e-9
Score:  0.185
Data Source:  BioPlex,STRINGDB
VDAC3
Tbio
Novelty:  0.0095068
p_int:  0.81407268
p_ni:  0.18592732
Score:  0.209
Data Source:  BioPlex,STRINGDB
FBXO39
Tbio
Novelty:  0.05342001
Score:  0.697
Data Source:  STRINGDB
ODF4
Tbio
Novelty:  0.13423621
Score:  0.687
Data Source:  STRINGDB
TSGA10
Tbio
Novelty:  0.04928862
Score:  0.61
Data Source:  STRINGDB
TENT5D
Tbio
Novelty:  0.1864027
Score:  0.597
Data Source:  STRINGDB
CCDC110
Tbio
Novelty:  0.11479518
Score:  0.595
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (18)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Parkinson disease
3
2
1
1.1
84.2
mathematical ability
3
1
3
73
educational attainment
1
4
4
70.4
alcohol consumption measurement
3
3
3
69.5
body mass index
2
1
2
63.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Parkinson disease
1
1.1
84.2
mathematical ability
3
73
educational attainment
4
70.4
alcohol consumption measurement
3
69.5
body mass index
2
63.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
spermatogenesis associated 19
VGNC:998
742829
Macaque
spermatogenesis associated 19
693524
Mouse
MGI:1922719
75469
Rat
RGD:620628
171403
Dog
spermatogenesis associated 19
VGNC:46707
479387
Species
Name
OMA
EggNOG
Inparanoid
Chimp
spermatogenesis associated 19
Macaque
spermatogenesis associated 19
Mouse
Rat
Dog
spermatogenesis associated 19
Publication Statistics
PubMed Score 19.66
PubMed score by year
PubTator Score 7.71
PubTator score by year
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Related Publications
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PMID
Year
Title