You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
SPARCL1
SPARC-like protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000282470
  • ENSP00000282470
  • ENSG00000152583
  • ENST00000418378
  • ENSP00000414856
  • ENST00000503414
  • ENSP00000422903

Symbol
  • SC1
  • MAST9
  • PIG33
  • MAST 9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.99
disease perturbation
0.93
PubMedID
0.92
small molecule perturbation
0.78
gene perturbation
0.67


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 138.13   (req: < 5)
Gene RIFs: 23   (req: <= 3)
Antibodies: 240   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 138.13   (req: >= 5)
Gene RIFs: 23   (req: > 3)
Antibodies: 240   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (164)
AMBN
Tbio
Novelty:  0.00354946
Score:  0.972
Data Source:  STRINGDB
SPP1
Tbio
Novelty:  0.00014418
Score:  0.961
Data Source:  STRINGDB
ENAM
Tbio
Novelty:  0.00593293
Score:  0.947
Data Source:  STRINGDB
GPC3
Tbio
Novelty:  0.00151823
Score:  0.943
Data Source:  STRINGDB
MEPE
Tbio
Novelty:  0.00825085
Score:  0.941
Data Source:  STRINGDB
AMTN
Tbio
Novelty:  0.02514528
Score:  0.941
Data Source:  STRINGDB
AMELX
Tbio
Novelty:  0.00063284
Score:  0.94
Data Source:  STRINGDB
FSTL1
Tbio
Novelty:  0.00557848
Score:  0.936
Data Source:  STRINGDB
FN1
Tchem
Novelty:  0.00003647
Score:  0.933
Data Source:  STRINGDB
FAM20C
Tbio
Family:  Enzyme
Novelty:  0.00318966
Score:  0.93
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Post-translational protein modification
Reactome
Post-translational protein phosphorylation
Reactome
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Post-translational protein modification
Post-translational protein phosphorylation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
3
4
4
89.8
SPARC-like protein 1 measurement
1
2
2
85.5
urate measurement
1
2
2
64.5
triglyceride measurement
1
1
1
46.7
intelligence
1
1
1
7.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
4
89.8
SPARC-like protein 1 measurement
2
85.5
urate measurement
2
64.5
triglyceride measurement
1
46.7
intelligence
1
7.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SPARC like 1
VGNC:1999
471247
Macaque
SPARC like 1
701468
Mouse
MGI:108110
13602
Rat
RGD:2531
25434
Horse
SPARC like 1
VGNC:23479
100052928
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SPARC like 1
Macaque
SPARC like 1
Mouse
Rat
Horse
SPARC like 1
Publication Statistics
PubMed Score 138.13
PubMed score by year
PubTator Score 41.26
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title