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Tdark
SPANXN4
Sperm protein associated with the nucleus on the X chromosome N4

Protein Summary
Description
This gene represents one of several duplicated family members that are located on the X chromosome. This gene family encodes proteins that play a role in spermiogenesis. These proteins represent a specific subgroup of cancer/testis-associated antigens, and they may be candidates for tumor vaccines. This family member belongs to a subgroup of related genes that are present in all primates and rats and mice, and thus, it represents one of the ancestral family members. [provided by RefSeq, Sep 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000446864
  • ENSP00000405210
  • ENSG00000189326

Symbol
  • CT11.9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.52
protein complex
0.4
interacting protein
0.38
cell line
0.37
tissue
0.25


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.13   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 12   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.13   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 12   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (85)
MAN2B2
Tbio
Family:  Enzyme
Novelty:  0.11499103
p_int:  0.999999897
p_ni:  1.03e-7
Data Source:  BioPlex
SSU72
Tbio
Family:  Enzyme
Novelty:  0.02342759
p_int:  0.999996118
p_ni:  0.000003871
p_wrong:  1.1e-8
Data Source:  BioPlex
ADO
Tbio
Family:  Enzyme
Novelty:  0.04529593
p_int:  0.999960255
p_ni:  0.000037662
p_wrong:  0.000002083
Data Source:  BioPlex
FAM120B
Tbio
Novelty:  0.07982799
p_int:  0.99990747
p_ni:  0.000092524
p_wrong:  6e-9
Data Source:  BioPlex
PNPO
Tchem
Family:  Enzyme
Novelty:  0.00919993
p_int:  0.999877878
p_ni:  0.000122122
Data Source:  BioPlex
MCMBP
Tbio
Novelty:  0.13330215
p_int:  0.999710165
p_ni:  0.000289835
Data Source:  BioPlex
CARNMT1
Tbio
Family:  Enzyme
Novelty:  0.28121779
p_int:  0.999698521
p_ni:  0.000301479
Data Source:  BioPlex
DCUN1D1
Tchem
Novelty:  0.03122408
p_int:  0.999606117
p_ni:  0.000043003
p_wrong:  0.000350881
Data Source:  BioPlex
KLHL18
Tdark
Novelty:  0.52915213
p_int:  0.999411977
p_ni:  0.000588013
p_wrong:  1e-8
Data Source:  BioPlex
MAPK8
Tchem
Family:  Kinase
Novelty:  0.00055723
p_int:  0.999274072
p_ni:  0.000725102
p_wrong:  8.26e-7
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
sperm protein associated with the nucleus on the X chromosome N4
740280
Macaque
sperm protein associated with the nucleus on the X chromosome N4
697888
Species
Name
OMA
EggNOG
Inparanoid
Chimp
sperm protein associated with the nucleus on the X chromosome N4
Macaque
sperm protein associated with the nucleus on the X chromosome N4
Publication Statistics
PubMed Score 0.13
PubMed score by year
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Related Publications
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PMID
Year
Title