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Tdark
SPANXN3
Sperm protein associated with the nucleus on the X chromosome N3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000370503
  • ENSP00000359534
  • ENSG00000189252

Symbol
  • CT11.8
  • SPANX-N3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.59
cellular component
0.52
disease
0.42
cell line
0.41
interacting protein
0.31


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.62   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 37   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.62   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 37   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (28)
FBXW2
Tbio
Novelty:  0.01492058
p_int:  0.999920494
p_ni:  0.000010641
p_wrong:  0.000068865
Score:  0.859
Data Source:  BioPlex,STRINGDB
BTRC
Tbio
Novelty:  0.00293475
p_int:  0.999498677
p_ni:  0.000501322
p_wrong:  1e-9
Score:  0.67
Data Source:  BioPlex,STRINGDB
FBXW11
Tbio
Novelty:  0.0715377
p_int:  0.999184948
p_ni:  0.000815052
Score:  0.241
Data Source:  BioPlex,STRINGDB
SUOX
Tbio
Family:  Enzyme
Novelty:  0.00971136
p_int:  0.998971263
p_ni:  0.001028708
p_wrong:  3e-8
Score:  0.513
Data Source:  BioPlex,STRINGDB
ARIH1
Tbio
Family:  Enzyme
Novelty:  0.0258739
p_int:  0.995990079
p_ni:  0.004009893
p_wrong:  2.8e-8
Score:  0.628
Data Source:  BioPlex,STRINGDB
CMSS1
Tdark
Novelty:  0.21418543
p_int:  0.943084456
p_ni:  0.056913989
p_wrong:  0.000001554
Score:  0.23
Data Source:  BioPlex,STRINGDB
CUL1
Tbio
Novelty:  0.00244476
p_int:  0.762264834
p_ni:  0.237735166
Score:  0.656
Data Source:  BioPlex,STRINGDB
SPANXD
Tdark
Novelty:  0.22064161
Score:  0.63
Data Source:  STRINGDB
SSX7
Tdark
Novelty:  3.926097
Score:  0.589
Data Source:  STRINGDB
XAGE3
Tdark
Novelty:  0.1418603
Score:  0.539
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
creatine kinase measurement
1
1
1
2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
creatine kinase measurement
1
2
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.62
PubMed score by year
PubTator Score 0.33
PubTator score by year
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Related Publications
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PMID
Year
Title