SP3
Transcription factor Sp3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.95 | ||
transcription factor binding site profile | 0.95 | ||
biological process | 0.9 | ||
virus perturbation | 0.88 | ||
hub protein | 0.85 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism of proteins | ||||
Reactome | Post-translational protein modification | ||||
Reactome | SUMO E3 ligases SUMOylate target proteins | ||||
Reactome | SUMOylation | ||||
Reactome | SUMOylation of transcription factors | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism of proteins | ||||
Post-translational protein modification | ||||
SUMO E3 ligases SUMOylate target proteins | ||||
SUMOylation | ||||
SUMOylation of transcription factors | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | ARUK-UCL | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
appendicular lean mass | 1 | 1 | 1 | 68.3 | |||||
red blood cell distribution width | 2 | 1 | 2 | 42.3 | |||||
1 | 1 | 0 | 1.1 | 27.3 | |||||
BMI-adjusted waist circumference | 1 | 1 | 1 | 24.5 | |||||
mean corpuscular volume | 1 | 1 | 1 | 17.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
appendicular lean mass | 1 | 68.3 | |||||
red blood cell distribution width | 2 | 42.3 | |||||
0 | 1.1 | 27.3 | |||||
BMI-adjusted waist circumference | 1 | 24.5 | |||||
mean corpuscular volume | 1 | 17.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | Sp3 transcription factor | VGNC:2817 | 459750 | |||||
Macaque | Sp3 transcription factor | 699901 | ||||||
Mouse | MGI:1277166 | 20687 | ||||||
Rat | RGD:1583765 | 367846 | ||||||
Dog | Sp3 transcription factor | VGNC:53107 | 488405 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | Sp3 transcription factor | |||||
Macaque | Sp3 transcription factor | |||||
Mouse | ||||||
Rat | ||||||
Dog | Sp3 transcription factor | |||||
PMID | Year | Title |
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