SOX17
Transcription factor SOX-17
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These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Deactivation of the beta-catenin transactivating complex | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by WNT | ||||
Reactome | TCF dependent signaling in response to WNT | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Deactivation of the beta-catenin transactivating complex | ||||
Signal Transduction | ||||
Signaling by WNT | ||||
TCF dependent signaling in response to WNT | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
low density lipoprotein cholesterol measurement | 6 | 3 | 9 | 89.1 | |||||
serum gamma-glutamyl transferase measurement | 2 | 2 | 2 | 88.8 | |||||
myeloid white cell count | 2 | 2 | 2 | 85.1 | |||||
total cholesterol measurement | 4 | 2 | 7 | 81.6 | |||||
4 | 4 | 2 | 1.4 | 79.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
low density lipoprotein cholesterol measurement | 9 | 89.1 | |||||
serum gamma-glutamyl transferase measurement | 2 | 88.8 | |||||
myeloid white cell count | 2 | 85.1 | |||||
total cholesterol measurement | 7 | 81.6 | |||||
2 | 1.4 | 79.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | SRY-box 17 | VGNC:1161 | 740572 | |||||
Mouse | MGI:107543 | 20671 | ||||||
Rat | RGD:1305371 | 312936 | ||||||
Dog | SRY-box 17 | VGNC:46676 | 486955 | |||||
Cow | SRY-box 17 | VGNC:35144 | 534010 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | SRY-box 17 | |||||
Mouse | ||||||
Rat | ||||||
Dog | SRY-box 17 | |||||
Cow | SRY-box 17 | |||||
PMID | Year | Title |
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