You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
SNRNP48
U11/U12 small nuclear ribonucleoprotein 48 kDa protein

Protein Summary
Description
Likely involved in U12-type 5' splice site recognition.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000342415
  • ENSP00000339834
  • ENSG00000168566

Symbol
  • C6orf151
  • C6orf151
  • dJ512B11.2
  • dJ336K20B.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.71
transcription factor binding site profile
0.67
tissue sample
0.61
transcription factor perturbation
0.61
virus perturbation
0.5


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.17   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 90   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.17   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 90   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (69)
PHF5A
Tbio
Family:  Epigenetic
Novelty:  0.02989472
p_int:  0.999999819
p_ni:  1.62e-7
p_wrong:  1.8e-8
Score:  0.72
Data Source:  BioPlex,STRINGDB
SNRPGP15
Tdark
p_int:  0.999998894
p_ni:  7.07e-7
p_wrong:  3.99e-7
Data Source:  BioPlex
SNRPN
Tbio
Novelty:  0.002157
p_int:  0.999997517
p_ni:  0.000002483
Score:  0.632
Data Source:  BioPlex,STRINGDB
ZRSR2
Tbio
Novelty:  0.03449891
p_int:  0.999993744
p_ni:  0.000006255
p_wrong:  1e-9
Score:  0.981
Data Source:  BioPlex,STRINGDB
ZCRB1
Tdark
Novelty:  0.37592387
p_int:  0.999991445
p_ni:  0.000008548
p_wrong:  7e-9
Score:  0.957
Data Source:  BioPlex,STRINGDB
SNRPF
Tdark
Novelty:  0.17624854
p_int:  0.999985684
p_ni:  0.000014316
Score:  0.952
Data Source:  BioPlex,STRINGDB
SNRPE
Tbio
Novelty:  0.02033423
p_int:  0.999967319
p_ni:  0.000032681
Score:  0.964
Data Source:  BioPlex,STRINGDB
ZMAT5
Tdark
Novelty:  0.97115324
p_int:  0.999819003
p_ni:  0.000180995
p_wrong:  2e-9
Score:  0.992
Data Source:  BioPlex,STRINGDB
SNRPB
Tbio
Novelty:  0.01503535
p_int:  0.998093191
p_ni:  0.001497635
p_wrong:  0.000409174
Score:  0.9
Data Source:  BioPlex,STRINGDB
SNRNP35
Tdark
Novelty:  1.00002211
p_int:  0.793351473
p_ni:  0.003352617
p_wrong:  0.203295909
Score:  0.993
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Metabolism of RNA (R-HSA-8953854)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of RNA
Reactome
Processing of Capped Intron-Containing Pre-mRNA
Reactome
mRNA Splicing
Reactome
mRNA Splicing - Minor Pathway
Name
Explore in Pharos
Explore in Source
Metabolism of RNA
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Minor Pathway
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
2
2
2
82.2
2
1
0
1.4
79.8
FEV/FEC ratio
1
1
1
75.2
1
1
0
1.4
71.9
BMI-adjusted hip circumference
2
2
2
50.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
2
82.2
0
1.4
79.8
FEV/FEC ratio
1
75.2
0
1.4
71.9
BMI-adjusted hip circumference
2
50.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
small nuclear ribonucleoprotein U11/U12 subunit 48
VGNC:8564
462421
Macaque
small nuclear ribonucleoprotein U11/U12 subunit 48
694974
Mouse
MGI:1915047
67797
Rat
RGD:1309020
291060
Dog
small nuclear ribonucleoprotein U11/U12 subunit 48
VGNC:46608
609283
Species
Name
OMA
EggNOG
Inparanoid
Chimp
small nuclear ribonucleoprotein U11/U12 subunit 48
Macaque
small nuclear ribonucleoprotein U11/U12 subunit 48
Mouse
Rat
Dog
small nuclear ribonucleoprotein U11/U12 subunit 48
Publication Statistics
PubMed Score 7.17
PubMed score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title