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Tbio
SNAPC1
snRNA-activating protein complex subunit 1

Protein Summary
Description
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000216294
  • ENSP00000216294
  • ENSG00000023608

Symbol
  • SNAP43
  • SNAP43
  • PTFgamma
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.62
cell line
0.61
tissue sample
0.6
transcription factor binding site profile
0.56
gene perturbation
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.74   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 164   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.74   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 164   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (124)
SNAPC3
Tbio
Novelty:  0.11748003
p_int:  0.999999999
Score:  0.999
Data Source:  BioPlex,STRINGDB
SNAPC4
Tbio
Family:  TF
Novelty:  0.09720791
p_int:  0.999999992
p_ni:  3e-9
p_wrong:  5e-9
Score:  0.999
Data Source:  BioPlex,STRINGDB
PSME3
Tbio
Novelty:  0.01051254
p_int:  0.999999694
p_ni:  1.5e-7
p_wrong:  1.56e-7
Score:  0.542
Data Source:  BioPlex,STRINGDB
ANKRD36B
Tdark
Novelty:  2.44907149
p_int:  0.999997601
p_ni:  0.000002393
p_wrong:  6e-9
Data Source:  BioPlex
SNAPC2
Tdark
Novelty:  0.26291137
p_int:  0.999993257
p_wrong:  0.000006743
Score:  0.995
Data Source:  BioPlex,STRINGDB
SNAPC5
Tdark
Novelty:  0.61681654
p_int:  0.999985996
p_ni:  3.9e-8
p_wrong:  0.000013964
Score:  0.992
Data Source:  BioPlex,STRINGDB
ZG16B
Tbio
Novelty:  0.08792924
p_int:  0.757056176
p_ni:  0.242936076
p_wrong:  0.000007748
Score:  0.185
Data Source:  BioPlex,STRINGDB
TBP
Tbio
Novelty:  0.00034941
Score:  0.972
Data Source:  STRINGDB
BRF2
Tbio
Novelty:  0.39111125
Score:  0.968
Data Source:  STRINGDB
POLR3F
Tbio
Family:  Enzyme
Novelty:  0.0805125
Score:  0.964
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (7)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 7
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
RNA Polymerase II Transcription
Reactome
RNA Polymerase III Abortive And Retractive Initiation
Reactome
RNA Polymerase III Transcription
Reactome
RNA Polymerase III Transcription Initiation
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
RNA Polymerase II Transcription
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription
RNA Polymerase III Transcription Initiation
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
2
2
77.4
body height
1
1
1
61.4
visceral adipose tissue measurement
1
1
1
40.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
77.4
body height
1
61.4
visceral adipose tissue measurement
1
40.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
small nuclear RNA activating complex polypeptide 1
VGNC:3314
100616509
Macaque
small nuclear RNA activating complex polypeptide 1
704797
Mouse
MGI:1922877
75627
Rat
RGD:1304671
314228
Dog
small nuclear RNA activating complex polypeptide 1
VGNC:46591
100856590
Species
Name
OMA
EggNOG
Inparanoid
Chimp
small nuclear RNA activating complex polypeptide 1
Macaque
small nuclear RNA activating complex polypeptide 1
Mouse
Rat
Dog
small nuclear RNA activating complex polypeptide 1
Publication Statistics
PubMed Score 5.74
PubMed score by year
PubTator Score 8.04
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title