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Tbio
SLIT3
Slit homolog 3 protein

Protein Summary
Description
May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors. The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000332966
  • ENSP00000332164
  • ENSG00000184347
  • ENST00000519560
  • ENSP00000430333

Symbol
  • KIAA0814
  • MEGF5
  • SLIL2
  • MEGF5
  • SLIL2
  • SLIT1
  • slit2
  • Slit-3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
1
trait
0.86
gene perturbation
0.72
PubMedID
0.7
transcription factor binding site profile
0.7


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 298.15   (req: < 5)
Gene RIFs: 24   (req: <= 3)
Antibodies: 219   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 298.15   (req: >= 5)
Gene RIFs: 24   (req: > 3)
Antibodies: 219   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 16
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0