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Tbio
SLCO5A1
Solute carrier organic anion transporter family member 5A1

Protein Summary
Description
This gene encodes a 12 transmembrane domain protein that is a member of the solute carrier organic anion transporter superfamily. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000260126
  • ENSP00000260126
  • ENSG00000137571
  • ENST00000524945
  • ENSP00000434422
  • ENST00000530307
  • ENSP00000431611

Symbol
  • OATP5A1
  • SLC21A15
  • OATPJ
  • OATP-J
  • OATP5A1
  • OATPRP4
  • OATP-RP4
  • SLC21A15
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.72
transcription factor binding site profile
0.68
cell line
0.67
transcription factor
0.64
PubMedID
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.34   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 31   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.34   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 31   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (27)
SULF1
Tbio
Family:  Enzyme
Novelty:  0.00992209
Score:  0.908
Data Source:  STRINGDB
LACTB2
Tbio
Family:  Enzyme
Novelty:  0.1868172
Score:  0.756
Data Source:  STRINGDB
XKR9
Tdark
Novelty:  0.57519937
Score:  0.744
Data Source:  STRINGDB
SLC22A14
Tdark
Family:  Transporter
Novelty:  0.3340737
Score:  0.738
Data Source:  STRINGDB
FAM83C
Tdark
Novelty:  0.67920174
Score:  0.679
Data Source:  STRINGDB
STAC
Tbio
Novelty:  0.01982527
Score:  0.672
Data Source:  STRINGDB
SLC17A8
Tbio
Family:  Transporter
Novelty:  0.00647654
Score:  0.637
Data Source:  STRINGDB
NCOA2
Tbio
Novelty:  0.00510052
Score:  0.63
Data Source:  STRINGDB
SLC6A9
Tchem
Family:  Transporter
Novelty:  0.05330871
Score:  0.614
Data Source:  STRINGDB
ABCB6
Tbio
Family:  Transporter
Novelty:  0.00552057
Score:  0.589
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
1
1
1
78.1
neutrophil count
1
1
1
66.3
leukocyte count
2
2
3
58.3
mosaic loss of chromosome Y measurement
1
1
1
50.6
basophil count
1
1
1
35
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
1
78.1
neutrophil count
1
66.3
leukocyte count
3
58.3
mosaic loss of chromosome Y measurement
1
50.6
basophil count
1
35
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier organic anion transporter family member 5A1
VGNC:7733
472788
Macaque
solute carrier organic anion transporter family member 5A1
705846
Mouse
MGI:2443431
240726
Rat
RGD:1307132
312907
Dog
solute carrier organic anion transporter family member 5A1
VGNC:46500
477907
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier organic anion transporter family member 5A1
Macaque
solute carrier organic anion transporter family member 5A1
Mouse
Rat
Dog
solute carrier organic anion transporter family member 5A1
Publication Statistics
PubMed Score 6.34
PubMed score by year
PubTator Score 5.15
PubTator score by year
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Related Publications
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PMID
Year
Title