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Tbio
SLC5A3
Sodium/myo-inositol cotransporter

Protein Summary
Description
Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000381151
  • ENSP00000370543
  • ENSG00000198743

Symbol
  • BCW2
  • SMIT
  • SMIT1
  • SMIT2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.99
microRNA
0.83
small molecule perturbation
0.76
transcription factor
0.69
gene perturbation
0.67


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 77.02   (req: < 5)
Gene RIFs: 14   (req: <= 3)
Antibodies: 196   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 77.02   (req: >= 5)
Gene RIFs: 14   (req: > 3)
Antibodies: 196   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0