Protein Summary
- ENST00000326019
- ENSP00000323837
- ENSG00000163798
- ENST00000613058
- ENSP00000479964
- HLC3
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.96 | ||
histone modification site profile | 0.89 | ||
kinase perturbation | 0.88 | ||
drug perturbation | 0.87 | ||
transcription factor binding site profile | 0.84 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.66 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 107 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.66 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 107 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (67)
PHF5A
Family: Epigenetic
Novelty: 0.02989472
p_int: 0.999999467
p_ni: 5.32e-7
Data Source: BioPlex
SNRPA1
Novelty: 0.01232044
p_int: 0.999992998
p_ni: 0.000007002
Score: 0.592
Data Source: BioPlex,STRINGDB
SNRPE
Novelty: 0.02033423
p_int: 0.999991627
p_ni: 0.000008367
p_wrong: 6e-9
Score: 0.359
Data Source: BioPlex,STRINGDB
RBM11
Novelty: 0.3223316
p_int: 0.999978062
p_ni: 0.000021938
Score: 0.269
Data Source: BioPlex,STRINGDB
SNRPN
Novelty: 0.002157
p_int: 0.999955658
p_ni: 0.000044342
Score: 0.551
Data Source: BioPlex,STRINGDB
RBM7
Novelty: 0.07482689
p_int: 0.99932317
p_ni: 0.00067683
Score: 0.188
Data Source: BioPlex,STRINGDB
TCEANC2
Novelty: 0.40325323
p_int: 0.998675332
p_ni: 0.001324668
Score: 0.181
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (5)
Functions (1)
Components (4)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations (null)
GWAS Traits (22)
Items per page:
1 – 5 of 22
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
triglyceride measurement | 3 | 7 | 7 | 97 | |||||
appendicular lean mass | 3 | 2 | 3 | 90.4 | |||||
C-reactive protein measurement | 1 | 3 | 3 | 89.3 | |||||
apolipoprotein B measurement | 1 | 2 | 2 | 71.1 | |||||
serum gamma-glutamyl transferase measurement | 1 | 1 | 1 | 70.5 | |||||
Items per page:
1 – 5 of 22
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
triglyceride measurement | 7 | 97 | |||||
appendicular lean mass | 3 | 90.4 | |||||
C-reactive protein measurement | 3 | 89.3 | |||||
apolipoprotein B measurement | 2 | 71.1 | |||||
serum gamma-glutamyl transferase measurement | 1 | 70.5 | |||||
Find similar targets by:
IDG Resources
Orthologs (15)
1 – 5 of 15
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | solute carrier family 4 member 1 adaptor protein | VGNC:7714 | 459111 | |||||
Macaque | solute carrier family 4 member 1 adaptor protein | 701783 | ||||||
Mouse | MGI:1196608 | 20534 | ||||||
Rat | RGD:1307080 | 298805 | ||||||
Dog | 39S ribosomal protein L33, mitochondrial [Source:RefSeq peptide;Acc:NP_001273997] | |||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | solute carrier family 4 member 1 adaptor protein | |||||
Macaque | solute carrier family 4 member 1 adaptor protein | |||||
Mouse | ||||||
Rat | ||||||
Dog | 39S ribosomal protein L33, mitochondrial [Source:RefSeq peptide;Acc:NP_001273997] | |||||
Publication Statistics
PubMed Score 3.66
PubMed score by year
PubTator Score 3.70
PubTator score by year
Related Publications
Text Mined References (21)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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