SLC44A2
Choline transporter-like protein 2
Protein Summary
Isoform 1, but not isoform 3, exhibits some choline transporter activity.
- ENST00000335757
- ENSP00000336888
- ENSG00000129353
- ENST00000407327
- ENSP00000385135
- ENST00000586078
- ENSP00000466664
- CTL2
- CTL2
- PP1292
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.99 | ||
transcription factor | 0.71 | ||
tissue | 0.64 | ||
tissue sample | 0.64 | ||
molecular function | 0.63 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 74.44 (req: < 5)
Gene RIFs: 21 (req: <= 3)
Antibodies: 127 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 74.44 (req: >= 5)
Gene RIFs: 21 (req: > 3)
Antibodies: 127 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (5)
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (120)
RP2
Novelty: 0.12345247
p_int: 0.999999181
p_ni: 1.44e-7
p_wrong: 6.75e-7
Score: 0.313
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (12)
Reactome (11)
KEGG (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Glycerophospholipid biosynthesis | ||||
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Glycerophospholipid biosynthesis | ||||
Immune System | ||||
Innate Immune System | ||||
Metabolism | ||||
Metabolism of lipids | ||||
Viral Interactions (0)
Gene Ontology Terms (11)
Functions (1)
Components (5)
Processes (5)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Traceable Author Statement (TAS) | UniProtKB | |||
Disease Associations (null)
GWAS Traits (29)
Items per page:
1 – 5 of 29
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
low density lipoprotein cholesterol measurement | 3 | 9 | 10 | 98.5 | |||||
apolipoprotein B measurement | 1 | 6 | 6 | 98 | |||||
total cholesterol measurement | 2 | 8 | 9 | 97.8 | |||||
red blood cell distribution width | 4 | 5 | 6 | 96.4 | |||||
reticulocyte measurement | 3 | 2 | 3 | 94.6 | |||||
Items per page:
1 – 5 of 29
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
low density lipoprotein cholesterol measurement | 10 | 98.5 | |||||
apolipoprotein B measurement | 6 | 98 | |||||
total cholesterol measurement | 9 | 97.8 | |||||
red blood cell distribution width | 6 | 96.4 | |||||
reticulocyte measurement | 3 | 94.6 | |||||
Find similar targets by:
IDG Resources
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | solute carrier family 44 member 2 | VGNC:7782 | 455711 | |||||
Macaque | solute carrier family 44 member 2 | 715866 | ||||||
Mouse | MGI:1915932 | 68682 | ||||||
Rat | RGD:1309680 | 363024 | ||||||
Dog | solute carrier family 44 member 2 | VGNC:46418 | 484951 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | solute carrier family 44 member 2 | |||||
Macaque | solute carrier family 44 member 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | solute carrier family 44 member 2 | |||||
Publication Statistics
PubMed Score 74.44
PubMed score by year
PubTator Score 42.09
PubTator score by year
Related Publications
Text Mined References (38)
GeneRif Annotations (21)
Items per page:
0 of 0
PMID | Year | Title |
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