Tbio SLC44A2 Choline transporter-like protein 2

Protein Summary

Description

Isoform 1, but not isoform 3, exhibits some choline transporter activity.

Uniprot Accession IDs

• Q8IWA5
• B2RBB1
• B3KNH3
• B4DFJ0
• F2Q9D7
• Q658V1
• Q658Z2
• Q6PJV7
• Q8N2F0
• Q9NY68

Gene Name

• SLC44A2

Ensembl ID

• ENST00000335757
• ENSP00000336888
• ENSG00000129353
• ENST00000407327
• ENSP00000385135
• ENST00000586078
• ENSP00000466664

Symbol

• CTL2
• CTL2
• PP1292

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.99
transcription factor	0.71
tissue	0.64
tissue sample	0.64
molecular function	0.63

Protein Classes

PANTHER Classes

Protein / Transporter / Choline Transporter-like Protein 2

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc44 Choline Transporter-like Family / Choline Transporter-like Protein 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 91.55   (req: < 5)

Gene RIFs: 21   (req: <= 3)

Antibodies: 127   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 91.55   (req: >= 5)

Gene RIFs: 21   (req: > 3)

Antibodies: 127   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0