SLC39A9
Zinc transporter ZIP9
Protein Summary
May act as a zinc-influx transporter.
- ENST00000336643
- ENSP00000336887
- ENSG00000029364
- ENST00000555840
- ENSP00000450639
- ENST00000556605
- ENSP00000452385
- ENST00000557046
- ENSP00000451833
- ZIP9
- ZIP9
- ZIP-9
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
kinase perturbation | 0.91 | ||
histone modification site profile | 0.81 | ||
transcription factor binding site profile | 0.76 | ||
virus perturbation | 0.76 | ||
microRNA | 0.69 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 21.32 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 120 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 21.32 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 120 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (91)
TPST2
Family: Enzyme
Novelty: 0.02551048
p_int: 0.99907765
p_ni: 0.00092231
p_wrong: 4e-8
Data Source: BioPlex
SLC25A24
Family: Transporter
Novelty: 0.06151955
p_int: 0.998477764
p_ni: 0.001522236
Score: 0.175
Data Source: BioPlex,STRINGDB
OSTC
Family: Enzyme
Novelty: 0.06699106
p_int: 0.998178083
p_ni: 0.001760272
p_wrong: 0.000061645
Data Source: BioPlex
HPCAL1
Novelty: 0.04434155
p_int: 0.998003165
p_ni: 0.001996561
p_wrong: 2.74e-7
Data Source: BioPlex
CANT1
Family: Enzyme
Novelty: 0.02640333
p_int: 0.997474841
p_ni: 0.002524794
p_wrong: 3.65e-7
Data Source: BioPlex
Nearest Tclin Targets
Pathways (3)
WikiPathways (3)
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
WikiPathways | Zinc homeostasis | ||||
WikiPathways | Nuclear Receptors Meta-Pathway | ||||
WikiPathways | NRF2 pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Zinc homeostasis | ||||
Nuclear Receptors Meta-Pathway | ||||
NRF2 pathway | ||||
Viral Interactions (0)
Gene Ontology Terms (3)
Functions (1)
Components (1)
Processes (1)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations ()
GWAS Traits (8)
Items per page:
1 – 5 of 8
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
neutrophil count | 2 | 2 | 2 | 89 | |||||
myeloid white cell count | 1 | 1 | 1 | 70.2 | |||||
neutrophil percentage of leukocytes | 1 | 1 | 1 | 68.6 | |||||
leukocyte count | 1 | 1 | 1 | 61.4 | |||||
lymphocyte percentage of leukocytes | 1 | 1 | 1 | 54.4 | |||||
Items per page:
1 – 5 of 8
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
neutrophil count | 2 | 89 | |||||
myeloid white cell count | 1 | 70.2 | |||||
neutrophil percentage of leukocytes | 1 | 68.6 | |||||
leukocyte count | 1 | 61.4 | |||||
lymphocyte percentage of leukocytes | 1 | 54.4 | |||||
Find similar targets by:
IDG Resources
Orthologs (15)
1 – 5 of 15
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | solute carrier family 39 member 9 | VGNC:8212 | 452998 | |||||
Macaque | solute carrier family 39 member 9 | 712430 | ||||||
Mouse | MGI:1914820 | 328133 | ||||||
Rat | RGD:1311236 | 314275 | ||||||
Dog | solute carrier family 39 member 9 | VGNC:46408 | 610146 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | solute carrier family 39 member 9 | |||||
Macaque | solute carrier family 39 member 9 | |||||
Mouse | ||||||
Rat | ||||||
Dog | solute carrier family 39 member 9 | |||||
Publication Statistics
PubMed Score 21.32
PubMed score by year
PubTator Score 9.99
PubTator score by year
Related Publications
Text Mined References (16)
GeneRif Annotations (7)
Items per page:
0 of 0
PMID | Year | Title |
|---|