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Tdark
SLC38A7
Putative sodium-coupled neutral amino acid transporter 7

Protein Summary
Description
Mediates sodium-dependent transport of amino acids, preferentially L-glutamine.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000219320
  • ENSP00000219320
  • ENSG00000103042
  • ENST00000570101
  • ENSP00000454646

Symbol
  • SNAT7
  • SNAT7
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.99
histone modification site profile
0.75
kinase perturbation
0.71
cell type or tissue
0.69
tissue sample
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.71   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 30   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.71   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 30   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (5)
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (65)
LAMP1
Tbio
Novelty:  0.00067563
p_int:  0.999964617
p_ni:  0.000035383
Score:  0.261
Data Source:  BioPlex,STRINGDB
PDPN
Tbio
Novelty:  0.00024118
p_int:  0.999950954
p_ni:  0.000003472
p_wrong:  0.000045573
Data Source:  BioPlex
CA14
Tclin
Family:  Enzyme
Novelty:  0.00864764
p_int:  0.999944619
p_ni:  0.000048157
p_wrong:  0.000007224
Data Source:  BioPlex
TCEA1
Tbio
Novelty:  0.00547888
p_int:  0.960831276
p_ni:  0.038406057
p_wrong:  0.000762666
Score:  0.167
Data Source:  BioPlex,STRINGDB
TMPRSS11B
Tdark
Family:  Enzyme
Novelty:  1.20690443
p_int:  0.941741427
p_ni:  0.00025455
p_wrong:  0.058004023
Data Source:  BioPlex
SLC22A6
Tclin
Family:  Transporter
Novelty:  0.00389149
p_int:  0.932305159
p_ni:  0.000348787
p_wrong:  0.067346054
Score:  0.19
Data Source:  BioPlex,STRINGDB
GGA1
Tbio
Novelty:  0.00866392
p_int:  0.912412373
p_ni:  0.087587627
p_wrong:  1e-9
Score:  0.183
Data Source:  BioPlex,STRINGDB
EEF1A2
Tchem
Novelty:  0.001472
p_int:  0.887439506
p_ni:  0.112560494
Data Source:  BioPlex
ETF1
Tbio
Family:  Enzyme
Novelty:  0.00711627
p_int:  0.875324373
p_ni:  0.124675627
Score:  0.219
Data Source:  BioPlex,STRINGDB
VRK1
Tbio
Family:  Kinase
Novelty:  0.00761136
p_int:  0.810771078
p_ni:  0.188164173
p_wrong:  0.00106475
Score:  0.19
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (16)
Find Similar Targets
Items per page:
10
1 – 10 of 11
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
QT interval
3
2
0
2
88.2
aspartate aminotransferase measurement
2
2
1
13.4
86.4
serum alanine aminotransferase measurement
1
1
1
53.7
3
3
0
1.1
44
apolipoprotein A 1 measurement
1
1
1
40.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
QT interval
0
2
88.2
aspartate aminotransferase measurement
1
13.4
86.4
serum alanine aminotransferase measurement
1
53.7
0
1.1
44
apolipoprotein A 1 measurement
1
40.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 38 member 7
VGNC:9013
454138
Macaque
solute carrier family 38 member 7
707671
Mouse
MGI:2679005
234595
Rat
RGD:1303268
291840
Dog
solute carrier family 38 member 7
VGNC:46397
487252
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 38 member 7
Macaque
solute carrier family 38 member 7
Mouse
Rat
Dog
solute carrier family 38 member 7
Publication Statistics
PubMed Score 5.71
PubMed score by year
PubTator Score 4.60
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title