You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
SLC35G2
Solute carrier family 35 member G2

Protein Summary
Description
May play a role in cell proliferation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000393079
  • ENSP00000376794
  • ENSG00000168917
  • ENST00000446465
  • ENSP00000400839

Symbol
  • TMEM22
  • TMEM22
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.87
cell type or tissue
0.68
kinase perturbation
0.66
tissue sample
0.63
PubMedID
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.88   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.88   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (5)
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (36)
SPPL2B
Tchem
Family:  Enzyme
Novelty:  0.0274774
p_int:  0.999915549
p_ni:  0.000075975
p_wrong:  0.000008475
Data Source:  BioPlex
MAS1
Tchem
Family:  GPCR
Novelty:  0.0089712
p_int:  0.9945707
p_ni:  0.000788149
p_wrong:  0.004641151
Data Source:  BioPlex
HTR2C
Tclin
Family:  GPCR
Novelty:  0.00074287
p_int:  0.980147284
p_ni:  0.000011204
p_wrong:  0.019841512
Data Source:  BioPlex
GRPR
Tchem
Family:  GPCR
Novelty:  0.00282511
p_int:  0.970269697
p_ni:  0.000122491
p_wrong:  0.029607812
Data Source:  BioPlex
CHRAC1
Tbio
Novelty:  0.17492099
p_int:  0.93440327
p_ni:  0.065121569
p_wrong:  0.000475161
Score:  0.228
Data Source:  BioPlex,STRINGDB
SLC15A1
Tchem
Family:  Transporter
Novelty:  0.00149723
p_int:  0.926007554
p_ni:  0.000067762
p_wrong:  0.073924684
Data Source:  BioPlex
DSCC1
Tbio
Novelty:  0.04747149
p_int:  0.779342477
p_ni:  0.220649287
p_wrong:  0.000008236
Score:  0.295
Data Source:  BioPlex,STRINGDB
DDX23
Tbio
Family:  Enzyme
Novelty:  0.03592096
p_int:  0.760993724
p_ni:  0.239006276
Data Source:  BioPlex
TMEM14A
Tbio
Novelty:  0.15995178
Score:  0.691
Data Source:  STRINGDB
SLC35C1
Tbio
Family:  Transporter
Novelty:  0.05958023
Score:  0.666
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (38)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
bilirubin measurement
2
1
2
83.8
neuroticism measurement
3
3
1
6.3
73.1
lymphocyte count
3
2
3
69.9
apolipoprotein B measurement
3
3
3
69.2
blood urea nitrogen measurement
1
1
1
69.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
bilirubin measurement
2
83.8
neuroticism measurement
1
6.3
73.1
lymphocyte count
3
69.9
apolipoprotein B measurement
3
69.2
blood urea nitrogen measurement
1
69.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member G2
VGNC:12188
742448
Macaque
solute carrier family 35 member G2
716881
Mouse
MGI:2685365
245020
Rat
RGD:1306109
315957
Dog
solute carrier family 35 member G2
VGNC:46381
485675
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member G2
Macaque
solute carrier family 35 member G2
Mouse
Rat
Dog
solute carrier family 35 member G2
Publication Statistics
PubMed Score 1.88
PubMed score by year
PubTator Score 0.77
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title