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Tdark
SLC35F1
Solute carrier family 35 member F1

Protein Summary
Description
Putative solute transporter.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000360388
  • ENSP00000353557
  • ENSG00000196376
  • ENST00000621341
  • ENSP00000484738

Symbol
  • C6orf169
  • C6orf169
  • dJ230I3.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.93
cell type or tissue
0.72
histone modification site profile
0.71
phenotype
0.62
microRNA
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.87   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 29   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.87   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 29   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (87)
VIPR2
Tchem
Family:  GPCR
Novelty:  0.00463802
p_int:  0.999829847
p_ni:  0.000133417
p_wrong:  0.000036735
Data Source:  BioPlex
HTR2C
Tclin
Family:  GPCR
Novelty:  0.00074287
p_int:  0.999715468
p_ni:  0.000129621
p_wrong:  0.00015491
Score:  0.197
Data Source:  BioPlex,STRINGDB
ATP5F1B
Tbio
Family:  Enzyme
Novelty:  0.01053177
p_int:  0.940923027
p_ni:  0.059076973
Score:  0.808
Data Source:  BioPlex,STRINGDB
NPY2R
Tchem
Family:  GPCR
Novelty:  0.01177255
p_int:  0.915959819
p_ni:  0.083643267
p_wrong:  0.000396914
Score:  0.206
Data Source:  BioPlex,STRINGDB
CEP85L
Tbio
Novelty:  0.23631446
Score:  0.709
Data Source:  STRINGDB
ATP8B3
Tdark
Family:  Transporter
Novelty:  0.44432131
Score:  0.672
Data Source:  STRINGDB
DIMT1
Tbio
Family:  Enzyme
Novelty:  0.1469259
Score:  0.662
Data Source:  STRINGDB
NOS1AP
Tbio
Family:  Enzyme
Novelty:  0.0076555
Score:  0.653
Data Source:  STRINGDB
SMG6
Tbio
Family:  Enzyme
Novelty:  0.0217417
Score:  0.625
Data Source:  STRINGDB
ZNF516
Tbio
Family:  TF
Novelty:  0.22650006
Score:  0.617
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
QT interval
6
5
4
1.8
93.7
3
3
0
1.1
89.8
electrocardiography
1
2
117
85.3
diastolic blood pressure
1
1
1
49.5
resting heart rate
1
1
0
6.3
39.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
QT interval
4
1.8
93.7
0
1.1
89.8
electrocardiography
117
85.3
diastolic blood pressure
1
49.5
resting heart rate
0
6.3
39.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member F1
VGNC:7928
472111
Macaque
solute carrier family 35 member F1
714965
Mouse
MGI:2139810
215085
Rat
RGD:1559576
502421
Dog
solute carrier family 35 member F1
VGNC:46375
484103
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member F1
Macaque
solute carrier family 35 member F1
Mouse
Rat
Dog
solute carrier family 35 member F1
Publication Statistics
PubMed Score 3.87
PubMed score by year
PubTator Score 0.91
PubTator score by year
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Related Publications
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PMID
Year
Title