Tbio SLC35B1 Solute carrier family 35 member B1

Protein Summary

Description

Probable sugar transporter. This gene encodes a nucleotide sugar transporter which is a member of solute carrier family 35. The transporters in this family are highly conserved hydrophobic proteins with multiple transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Uniprot Accession IDs

• P78383
• B4DEC4
• J3KQV4
• Q96EW7

Gene Name

• SLC35B1

Ensembl ID

• ENST00000240333
• ENSP00000240333
• ENSG00000121073
• ENST00000649906
• ENSP00000497423

Symbol

• UGTREL1
• UGTREL1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	1
kinase perturbation	0.95
virus perturbation	0.94
transcription factor binding site profile	0.9
histone modification site profile	0.83

Protein Classes

PANTHER Classes

Protein / Transporter / Solute Carrier Family 35 Member B1

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc35 Family Of Nucleotide Sugar Transporters / Solute Carrier Family 35 Member B1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.04   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 62   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.04   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 62   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0