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Tbio
SLC35A2
UDP-galactose translocator

Protein Summary
Description
Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function. This gene encodes a member of the nucleotide-sugar transporter family. The encoded protein is a multi-pass membrane protein. It transports UDP-galactose from the cytosol into Golgi vesicles, where it serves as a glycosyl donor for the generation of glycans. Mutations in this gene cause congenital disorder of glycosylation type IIm (CDG2M). Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000247138
  • ENSP00000247138
  • ENSG00000102100
  • ENST00000376521
  • ENSP00000365704
  • ENST00000445167
  • ENSP00000402726
  • ENST00000452555
  • ENSP00000416002
  • ENST00000635285
  • ENSP00000489484
  • ENST00000635589
  • ENSP00000489197

Symbol
  • UGALT
  • UGT
  • UGTL
  • UGT
  • CDGX
  • UGAT
  • UGT1
  • UGT2
  • UGTL
  • CDG2M
  • UGALT
  • UDP-Gal-Tr
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.99
molecular function
0.84
tissue
0.7
transcription factor
0.69
cellular component
0.66


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1565.45   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 57   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1565.45   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0