SLC34A1
Sodium-dependent phosphate transport protein 2A
Protein Summary
Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx. This gene encodes a member of the type II sodium-phosphate cotransporter family. Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
- ENST00000324417
- ENSP00000321424
- ENSG00000131183
- ENST00000512593
- ENSP00000423022
- NPT2
- SLC17A2
- NPT2
- FRTS2
- SLC11
- HCINF2
- NAPI-3
- NPTIIa
- NPHLOP1
- SLC17A2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
biological process | 0.94 | ||
molecular function | 0.76 | ||
cellular component | 0.66 | ||
cell type or tissue | 0.61 | ||
tissue sample | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 120.58 (req: < 5)
Gene RIFs: 35 (req: <= 3)
Antibodies: 136 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 120.58 (req: >= 5)
Gene RIFs: 35 (req: > 3)
Antibodies: 136 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 36
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 7
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0