Tbio SLC30A2 Zinc transporter 2

Protein Summary

Description

The protein encoded by this gene is a zinc transporter that acts as a homodimer. The encoded protein plays a role in secreting zinc into breast milk. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

Uniprot Accession IDs

• Q9BRI3
• Q71RC8
• ZnT-2

Gene Name

• SLC30A2

Ensembl ID

• ENST00000374276
• ENSP00000363394
• ENSG00000158014
• ENST00000374278
• ENSP00000363396

Symbol

• ZNT2
• TNZD
• ZNT2
• ZnT-2
• PP12488

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.93
PubMedID	0.66
cellular component	0.63
tissue	0.49
transcription factor	0.48

Protein Classes

PANTHER Classes

Protein / Transporter / Zinc Transporter 2

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc30 Zinc Transporter Family / Zinc Transporter 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 62.71   (req: < 5)

Gene RIFs: 22   (req: <= 3)

Antibodies: 41   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 62.71   (req: >= 5)

Gene RIFs: 22   (req: > 3)

Antibodies: 41   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0