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Tbio
SLC25A51
Solute carrier family 25 member 51

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000242275
  • ENSP00000242275
  • ENSG00000122696
  • ENST00000377716
  • ENSP00000366945

Symbol
  • MCART1
  • CG7943
  • MCART1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.91
kinase perturbation
0.81
histone modification site profile
0.77
virus perturbation
0.76
trait
0.75


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.79   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 96   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.79   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 96   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (5)
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (53)
MRAP2
Tbio
Novelty:  0.0420503
p_int:  0.999995577
p_ni:  0.000004422
p_wrong:  1e-9
Data Source:  BioPlex
CD27
Tbio
Novelty:  0.00090508
p_int:  0.999988721
p_ni:  0.000011277
p_wrong:  2e-9
Score:  0.205
Data Source:  BioPlex,STRINGDB
EVA1B
Tdark
Novelty:  2.1380272
p_int:  0.999986087
p_ni:  0.000013911
p_wrong:  2e-9
Data Source:  BioPlex
FAM234B
Tdark
Novelty:  1.53957047
p_int:  0.999984161
p_ni:  0.000015839
Data Source:  BioPlex
SCN2B
Tbio
Family:  IC
Novelty:  0.03773629
p_int:  0.99997575
p_ni:  0.000024246
p_wrong:  4e-9
Data Source:  BioPlex
KCNC4
Tclin
Family:  IC
Novelty:  0.01215128
p_int:  0.999896896
p_ni:  0.000103103
p_wrong:  2e-9
Data Source:  BioPlex
SLC22A9
Tbio
Family:  Transporter
Novelty:  0.02212992
p_int:  0.999890148
p_ni:  0.000109846
p_wrong:  7e-9
Data Source:  BioPlex
CTLA4
Tclin
Novelty:  0.00012781
p_int:  0.999864962
p_ni:  0.000130865
p_wrong:  0.000004173
Data Source:  BioPlex
BTNL3
Tdark
Novelty:  0.27343899
p_int:  0.99981364
p_ni:  0.000186347
p_wrong:  1.3e-8
Score:  0.188
Data Source:  BioPlex,STRINGDB
SLC39A5
Tbio
Family:  Transporter
Novelty:  0.05205571
p_int:  0.995784589
p_ni:  0.002406794
p_wrong:  0.001808616
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte count
2
2
2
47.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte count
2
47.5
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 25 member 51
VGNC:13961
748270
Macaque
solute carrier family 25 member 51
716206
Mouse
MGI:2684984
230125
Rat
RGD:6502452
100909697
Dog
solute carrier family 25 member 51
100686420
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 25 member 51
Macaque
solute carrier family 25 member 51
Mouse
Rat
Dog
solute carrier family 25 member 51
Publication Statistics
PubMed Score 5.79
PubMed score by year
PubTator Score 1.04
PubTator score by year
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Related Publications
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PMID
Year
Title