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Tbio
SLC25A43
Solute carrier family 25 member 43

Protein Summary
Description
This gene encodes a member of the mitochondrial carrier family of proteins.[provided by RefSeq, Dec 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000217909
  • ENSP00000217909
  • ENSG00000077713
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.78
tissue sample
0.62
microRNA
0.59
cellular component
0.48
cell line
0.44


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.72   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 16   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.72   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 16   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (5)
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
PROSER2
Tdark
Novelty:  0.56334611
p_int:  0.999999638
p_ni:  3.62e-7
Score:  0.189
Data Source:  BioPlex,STRINGDB
NDEL1
Tbio
Novelty:  0.01241819
p_int:  0.99907103
p_ni:  0.00092897
Data Source:  BioPlex
HSPD1
Tbio
Novelty:  0.00018924
p_int:  0.880050437
p_ni:  0.119949563
Score:  0.185
Data Source:  BioPlex,STRINGDB
SEPT6
Tbio
Novelty:  0.00885503
Score:  0.779
Data Source:  STRINGDB
RNF113A
Tbio
Novelty:  0.08315032
Score:  0.751
Data Source:  STRINGDB
MAP3K15
Tchem
Family:  Kinase
Novelty:  0.12112018
Score:  0.684
Data Source:  STRINGDB
ADGRG4
Tdark
Family:  GPCR
Novelty:  0.39161511
Score:  0.654
Data Source:  STRINGDB
FRMD7
Tbio
Novelty:  0.01561885
Score:  0.637
Data Source:  STRINGDB
CXorf56
Tdark
Novelty:  0.39137617
Score:  0.636
Data Source:  STRINGDB
DOCK11
Tdark
Novelty:  0.0295159
Score:  0.627
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
1
1
32.7
glomerular filtration rate
1
1
0
6.2
5.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
32.7
glomerular filtration rate
0
6.2
5.8
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
solute carrier family 25 member 5
693502
Mouse
MGI:2684854
194744
Rat
RGD:1559928
298318
Dog
solute carrier family 25 member 43
VGNC:46314
481030
Cow
solute carrier family 25 member 43
VGNC:34768
535541
Species
Name
OMA
EggNOG
Inparanoid
Macaque
solute carrier family 25 member 5
Mouse
Rat
Dog
solute carrier family 25 member 43
Cow
solute carrier family 25 member 43
Publication Statistics
PubMed Score 5.72
PubMed score by year
PubTator Score 5.33
PubTator score by year
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Related Publications
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PMID
Year
Title