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Tbio
SLC22A9
Solute carrier family 22 member 9

Protein Summary
Description
Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000279178
  • ENSP00000279178
  • ENSG00000149742
  • ENST00000536333
  • ENSP00000440206

Symbol
  • hOAT4
  • OAT7
  • UST3
  • OAT4
  • OAT7
  • ust3
  • HOAT4
  • UST3H
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.85
chemical
0.68
cell line
0.62
molecular function
0.6
disease
0.48


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 50.92   (req: < 5)
Gene RIFs: 11   (req: <= 3)
Antibodies: 51   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 50.92   (req: >= 5)
Gene RIFs: 11   (req: > 3)
Antibodies: 51   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0