Tbio SLC22A13 Solute carrier family 22 member 13

Protein Summary

Description

This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine. [provided by RefSeq, Sep 2008]

Uniprot Accession IDs

• Q9Y226
• B2RCV9
• Q8IYG1

Gene Name

• SLC22A13

Ensembl ID

• ENST00000311856
• ENSP00000310241
• ENSG00000172940

Symbol

• OCTL1
• ORCTL3
• OAT10
• OCTL1
• OCTL3
• ORCTL3
• ORCTL-3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.79
tissue sample	0.6
kinase perturbation	0.54
tissue	0.49
gene perturbation	0.42

Protein Classes

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc22 Family Of Organic Cation And Anion Transporters / Orphan Or Poorly Characterized Slc22 Family Members / Solute Carrier Family 22 Member 13

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.49   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 72   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.49   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0