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Tchem
SLC1A7
Excitatory amino acid transporter 5

Protein Summary
Description
Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371491
  • ENSP00000360546
  • ENSG00000162383
  • ENST00000371494
  • ENSP00000360549

Symbol
  • EAAT5
  • AAAT
  • EAAT5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.9
cell line
0.7
tissue
0.55
cell type or tissue
0.53
tissue sample
0.51


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1312.77   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 116   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1312.77   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 116   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 2
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0