SLC17A9
Solute carrier family 17 member 9
Protein Summary
Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles. This gene encodes a member of a family of transmembrane proteins that are involved in the transport of small molecules. The encoded protein participates in the vesicular uptake, storage, and secretion of adenoside triphosphate (ATP) and other nucleotides. A mutation in this gene was found in individuals with autosomal dominant disseminated superficial actinic porokeratosis-8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
- ENST00000370349
- ENSP00000359374
- ENSG00000101194
- ENST00000370351
- ENSP00000359376
- C20orf59
- VNUT
- POROK8
- C20orf59
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor binding site profile | 0.66 | ||
cell type or tissue | 0.6 | ||
PubMedID | 0.6 | ||
gene perturbation | 0.55 | ||
transcription factor perturbation | 0.54 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 65.69 (req: < 5)
Gene RIFs: 8 (req: <= 3)
Antibodies: 16 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 65.69 (req: >= 5)
Gene RIFs: 8 (req: > 3)
Antibodies: 16 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 1
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (5)
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (1)
Active Ligands (0)
Protein-Protein Interactions (25)
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (1)
Components (1)
Processes (2)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations (null)
GWAS Traits (2)
Items per page:
1 – 2 of 2
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
monocyte count | 1 | 1 | 1 | 48.5 | |||||
age at menopause | 1 | 1 | 1 | 42.3 | |||||
Items per page:
1 – 2 of 2
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
monocyte count | 1 | 48.5 | |||||
age at menopause | 1 | 42.3 | |||||
Find similar targets by:
IDG Resources
Orthologs (14)
1 – 5 of 14
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | solute carrier family 17 member 9 | VGNC:9983 | 738781 | |||||
Mouse | MGI:1919107 | 228993 | ||||||
Rat | RGD:1311940 | 362287 | ||||||
Dog | solute carrier family 17 member 9 | VGNC:46254 | 485966 | |||||
Horse | solute carrier family 17 member 9 | VGNC:23054 | 100058964 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | solute carrier family 17 member 9 | |||||
Mouse | ||||||
Rat | ||||||
Dog | solute carrier family 17 member 9 | |||||
Horse | solute carrier family 17 member 9 | |||||
Publication Statistics
PubMed Score 65.69
PubMed score by year
PubTator Score 20.72
PubTator score by year
Related Publications
Text Mined References (16)
GeneRif Annotations (8)
Items per page:
0 of 0
PMID | Year | Title |
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