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Tbio
SLC16A14
Monocarboxylate transporter 14

Protein Summary
Description
Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295190
  • ENSP00000295190
  • ENSG00000163053

Symbol
  • MCT14
  • MCT14
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.97
transcription factor binding site profile
0.73
microRNA
0.66
transcription factor perturbation
0.61
cell type or tissue
0.59


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.13   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 68   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.13   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 68   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (5)
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
GNAQ
Tbio
Novelty:  0.0008997
p_int:  0.780866276
p_ni:  0.219131572
p_wrong:  0.000002152
Score:  0.228
Data Source:  BioPlex,STRINGDB
SVIP
Tbio
Novelty:  0.05269453
p_int:  0.759726687
p_ni:  0.180677751
p_wrong:  0.059595562
Score:  0.269
Data Source:  BioPlex,STRINGDB
CAB39
Tbio
Novelty:  0.01592402
Score:  0.633
Data Source:  STRINGDB
SLC5A12
Tdark
Family:  Transporter
Novelty:  0.12119749
Score:  0.613
Data Source:  STRINGDB
EMB
Tbio
Novelty:  0.00135577
Score:  0.594
Data Source:  STRINGDB
SLC5A8
Tchem
Family:  Transporter
Novelty:  0.00892277
Score:  0.585
Data Source:  STRINGDB
SLC25A26
Tbio
Family:  Transporter
Novelty:  0.08598674
Score:  0.524
Data Source:  STRINGDB
CYYR1
Tbio
Novelty:  0.19732526
Score:  0.519
Data Source:  STRINGDB
BSG
Tbio
Novelty:  0.0010285
Score:  0.518
Data Source:  STRINGDB
MFSD11
Tdark
Novelty:  0.13167358
Score:  0.512
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
1
1
59.5
serum non-albumin protein measurement
1
2
2
46.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
59.5
serum non-albumin protein measurement
2
46.9
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
solute carrier family 16 member 14
710743
Mouse
MGI:1919031
71781
Rat
RGD:1309675
316578
Dog
solute carrier family 16 member 14
VGNC:46240
486154
Horse
solute carrier family 16 member 14
VGNC:23040
100063374
Species
Name
OMA
EggNOG
Inparanoid
Macaque
solute carrier family 16 member 14
Mouse
Rat
Dog
solute carrier family 16 member 14
Horse
solute carrier family 16 member 14
Publication Statistics
PubMed Score 12.13
PubMed score by year
PubTator Score 6.46
PubTator score by year
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Related Publications
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PMID
Year
Title