SLC15A4
Solute carrier family 15 member 4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.88 | ||
transcription factor perturbation | 0.88 | ||
virus perturbation | 0.85 | ||
transcription factor binding site profile | 0.79 | ||
molecular function | 0.76 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Reactome | Neutrophil degranulation | ||||
Reactome | Proton/oligopeptide cotransporters | ||||
Reactome | SLC-mediated transmembrane transport | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Immune System | ||||
Innate Immune System | ||||
Neutrophil degranulation | ||||
Proton/oligopeptide cotransporters | ||||
SLC-mediated transmembrane transport | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
6 | 5 | 0 | 1.2 | 78.5 | |||||
basophil percentage of leukocytes | 1 | 1 | 1 | 67.9 | |||||
basophil count | 2 | 1 | 2 | 57.8 | |||||
age at onset | 1 | 1 | 0 | 2.9 | 24.5 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.2 | 78.5 | |||||
basophil percentage of leukocytes | 1 | 67.9 | |||||
basophil count | 2 | 57.8 | |||||
age at onset | 0 | 2.9 | 24.5 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | solute carrier family 15 member 4 | VGNC:8534 | 452366 | |||||
Macaque | solute carrier family 15 member 4 | 716359 | ||||||
Mouse | MGI:2140796 | 100561 | ||||||
Rat | RGD:708469 | 246280 | ||||||
Dog | solute carrier family 15 member 4 | VGNC:52967 | 610055 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | solute carrier family 15 member 4 | |||||
Macaque | solute carrier family 15 member 4 | |||||
Mouse | ||||||
Rat | ||||||
Dog | solute carrier family 15 member 4 | |||||
PMID | Year | Title |
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