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Tbio
SLC12A8
Solute carrier family 12 member 8

Protein Summary
Description
Cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation. This gene is thought to be a candidate for psoriasis susceptibility. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Sep 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000393469
  • ENSP00000377112
  • ENSG00000221955
  • ENST00000430155
  • ENSP00000415713
  • ENST00000469902
  • ENSP00000418783

Symbol
  • CCC9
  • CCC9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.85
transcription factor
0.73
histone modification site profile
0.72
PubMedID
0.71
transcription factor perturbation
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.96   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 36   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.96   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0