SLC12A6
Solute carrier family 12 member 6
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.76 | ||
protein domain | 0.73 | ||
tissue sample | 0.72 | ||
kinase perturbation | 0.71 | ||
transcription factor | 0.71 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cation-coupled Chloride cotransporters | ||||
Reactome | Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) | ||||
Reactome | Disease | ||||
Reactome | Disorders of transmembrane transporters | ||||
Reactome | SLC transporter disorders | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cation-coupled Chloride cotransporters | ||||
Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) | ||||
Disease | ||||
Disorders of transmembrane transporters | ||||
SLC transporter disorders | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | ParkinsonsUK-UCL | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | ParkinsonsUK-UCL | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 1 | 1 | 1 | 49.5 | |||||
refractive error measurement | 1 | 2 | 2 | 43.9 | |||||
self reported educational attainment | 2 | 1 | 2 | 12.9 | |||||
intelligence | 1 | 1 | 1 | 9.5 | |||||
1 | 1 | 1 | 9.5 | ||||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean platelet volume | 1 | 49.5 | |||||
refractive error measurement | 2 | 43.9 | |||||
self reported educational attainment | 2 | 12.9 | |||||
intelligence | 1 | 9.5 | |||||
1 | 9.5 | ||||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | solute carrier family 12 member 6 | VGNC:7778 | 750207 | |||||
Macaque | solute carrier family 12 member 6 | 697536 | ||||||
Mouse | MGI:2135960 | 107723 | ||||||
Rat | RGD:1311335 | 691209 | ||||||
Dog | solute carrier family 12 member 6 | VGNC:46223 | 478239 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | solute carrier family 12 member 6 | |||||
Macaque | solute carrier family 12 member 6 | |||||
Mouse | ||||||
Rat | ||||||
Dog | solute carrier family 12 member 6 | |||||
PMID | Year | Title |
---|