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Tbio
SLC10A7
Sodium/bile acid cotransporter 7

Protein Summary
Description
Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000335472
  • ENSP00000334594
  • ENSG00000120519
  • ENST00000394059
  • ENSP00000377623
  • ENST00000432059
  • ENSP00000411297
  • ENST00000502607
  • ENSP00000422577
  • ENST00000507030
  • ENSP00000421275
  • ENST00000511374
  • ENSP00000421603

Symbol
  • C4orf13
  • P7
  • P7
  • SSASKS
  • C4orf13
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.92
microRNA
0.83
transcription factor binding site profile
0.81
kinase perturbation
0.66
transcription factor
0.66


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.41   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 88   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.41   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (5)
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (44)
DPY19L4
Tdark
Family:  Enzyme
Novelty:  0.99997412
p_int:  0.9999678
p_ni:  0.000032199
Score:  0.163
Data Source:  BioPlex,STRINGDB
ATP6V0D1
Tbio
Family:  Enzyme
Novelty:  0.05146108
p_int:  0.988413227
p_ni:  0.011586773
Data Source:  BioPlex
CD79A
Tbio
Novelty:  0.00118942
p_int:  0.984884301
p_ni:  0.014898479
p_wrong:  0.00021722
Data Source:  BioPlex
MME
Tclin
Family:  Enzyme
Novelty:  0.00019144
p_int:  0.979076437
p_ni:  0.020015103
p_wrong:  0.00090846
Data Source:  BioPlex
ISLR
Tbio
Novelty:  0.02936208
p_int:  0.967597552
p_ni:  0.031753841
p_wrong:  0.000648607
Score:  0.207
Data Source:  BioPlex,STRINGDB
PCDHA4
Tdark
Novelty:  0.30511211
p_int:  0.959297984
p_ni:  0.040434488
p_wrong:  0.000267527
Data Source:  BioPlex
IQCF1
Tdark
Novelty:  0.78525464
p_int:  0.937023613
p_ni:  0.062403697
p_wrong:  0.00057269
Data Source:  BioPlex
EIF2B2
Tbio
Novelty:  0.03253919
p_int:  0.930485389
p_ni:  0.069514444
p_wrong:  1.67e-7
Data Source:  BioPlex
Q8NFQ8
Tbio
Novelty:  0.08912351
p_int:  0.929070539
p_ni:  0.070642748
p_wrong:  0.000286713
Data Source:  BioPlex
ECPAS
Tbio
Novelty:  0.04004664
p_int:  0.928006994
p_ni:  0.071993006
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
1
1
1
45.9
1
1
1
42.5
1
1
1
42.5
body height
1
1
1
23.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
1
45.9
1
42.5
1
42.5
body height
1
23.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 10 member 7
VGNC:12977
101056859
Macaque
solute carrier family 10 member 7
703452
Mouse
MGI:1924025
76775
Rat
RGD:1564388
291942
Dog
solute carrier family 10 member 7
VGNC:46215
612344
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 10 member 7
Macaque
solute carrier family 10 member 7
Mouse
Rat
Dog
solute carrier family 10 member 7
Publication Statistics
PubMed Score 11.41
PubMed score by year
PubTator Score 99.51
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title