You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
SIRPD
Signal-regulatory protein delta

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 93   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 93   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (20)
EPDR1
Tbio
Novelty:  0.03597825
p_int:  0.993692909
p_ni:  0.00630618
p_wrong:  9.11e-7
Score:  0.209
Data Source:  BioPlex,STRINGDB
DIRAS2
Tbio
Family:  Enzyme
Novelty:  0.12334631
p_int:  0.982080654
p_ni:  0.017688993
p_wrong:  0.000230353
Score:  0.282
Data Source:  BioPlex,STRINGDB
HIKESHI
Tbio
Novelty:  0.0683189
p_int:  0.90703592
p_ni:  0.090362362
p_wrong:  0.002601718
Score:  0.332
Data Source:  BioPlex,STRINGDB
NT5C
Tbio
Family:  Enzyme
Novelty:  0.00686933
p_int:  0.776472105
p_ni:  0.223527314
p_wrong:  5.81e-7
Score:  0.309
Data Source:  BioPlex,STRINGDB
FAM162B
Tdark
Novelty:  1.43078788
Score:  0.589
Data Source:  STRINGDB
C2orf74
Tdark
Novelty:  1.10883293
Score:  0.589
Data Source:  STRINGDB
KIAA1841
Tdark
Novelty:  1.50148602
Score:  0.585
Data Source:  STRINGDB
ZUP1
Tbio
Family:  Enzyme
Novelty:  0.21515695
Score:  0.583
Data Source:  STRINGDB
ZNF687
Tbio
Family:  TF
Novelty:  0.14707532
Score:  0.542
Data Source:  STRINGDB
MINDY4
Tdark
Novelty:  0.55864743
Score:  0.539
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
2
3
4
96.1
platelet crit
2
2
2
84.6
monocyte count
1
1
1
75.3
2
2
0
1.1
63
neutrophil count
2
1
2
44.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
4
96.1
platelet crit
2
84.6
monocyte count
1
75.3
0
1.1
63
neutrophil count
2
44.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
signal regulatory protein delta
VGNC:14293
100614474
Species
Name
OMA
EggNOG
Inparanoid
Chimp
signal regulatory protein delta
Publication Statistics
PubMed Score 0.27
PubMed score by year
PubTator Score 0.65
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title