SIK2
Serine/threonine-protein kinase SIK2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
drug perturbation | 0.99 | ||
molecular function | 0.95 | ||
protein domain | 0.92 | ||
virus perturbation | 0.92 | ||
interacting protein | 0.84 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
KEGG | Glucagon signaling pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Glucagon signaling pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 4 | 5 | 6 | 95.6 | |||||
waist-hip ratio | 2 | 5 | 5 | 93.4 | |||||
BMI-adjusted waist circumference | 1 | 6 | 6 | 92.6 | |||||
waist circumference | 1 | 4 | 4 | 91 | |||||
6 | 5 | 0 | 1 | 88.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 6 | 95.6 | |||||
waist-hip ratio | 5 | 93.4 | |||||
BMI-adjusted waist circumference | 6 | 92.6 | |||||
waist circumference | 4 | 91 | |||||
0 | 1 | 88.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | salt inducible kinase 2 | VGNC:3236 | 451540 | |||||
Macaque | salt inducible kinase 2 [Source:HGNC Symbol;Acc:HGNC:21680] | |||||||
Mouse | MGI:2445031 | 235344 | ||||||
Rat | RGD:1559698 | 315649 | ||||||
Dog | salt inducible kinase 2 | VGNC:53440 | 489410 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | salt inducible kinase 2 | |||||
Macaque | salt inducible kinase 2 [Source:HGNC Symbol;Acc:HGNC:21680] | |||||
Mouse | ||||||
Rat | ||||||
Dog | salt inducible kinase 2 | |||||
PMID | Year | Title |
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