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Tdark
SIGLECL1
SIGLEC family-like protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000316401
  • ENSP00000321249
  • ENSG00000179213
  • ENST00000614422
  • ENSP00000480286

Symbol
  • C19orf75
  • C19orf75
  • SIGLECP7
  • SIGLEC23P
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.5
phenotype
0.37
tissue
0.37
microRNA
0.36
cellular component
0.29


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 79   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 79   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (96)
MIGA2
Tbio
Novelty:  0.20807703
p_int:  0.999997542
p_ni:  0.000002398
p_wrong:  6e-8
Data Source:  BioPlex
TNPO2
Tbio
Novelty:  0.10454262
p_int:  0.999991118
p_ni:  0.000008882
Data Source:  BioPlex
VPS8
Tbio
Novelty:  0.05178496
p_int:  0.999986626
p_ni:  0.000013374
Data Source:  BioPlex
MIGA1
Tbio
Novelty:  0.08346483
p_int:  0.999945826
p_ni:  0.000054174
Data Source:  BioPlex
TBC1D22B
Tbio
Novelty:  0.49852962
p_int:  0.999936862
p_ni:  0.000063137
p_wrong:  1e-9
Data Source:  BioPlex
GSDME
Tbio
Novelty:  0.01231123
p_int:  0.999926481
p_ni:  0.000073519
Data Source:  BioPlex
BTAF1
Tbio
Novelty:  0.01586704
p_int:  0.999914027
p_ni:  0.000085973
Data Source:  BioPlex
IPO9
Tbio
Novelty:  0.03978028
p_int:  0.999846311
p_ni:  0.000153689
Data Source:  BioPlex
STAG1
Tbio
Novelty:  0.00122511
p_int:  0.999755219
p_ni:  0.000244781
Data Source:  BioPlex
MPZL1
Tbio
Novelty:  0.03292508
p_int:  0.999731078
p_ni:  0.000268865
p_wrong:  5.8e-8
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (21)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
myeloid white cell count
13
7
13
96
blood protein measurement
4
7
7
91.2
C-reactive protein measurement
3
3
3
87.1
lymphocyte count
3
2
3
75.8
leukocyte count
3
2
3
74.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
myeloid white cell count
13
96
blood protein measurement
7
91.2
C-reactive protein measurement
3
87.1
lymphocyte count
3
75.8
leukocyte count
3
74.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Dog
SIGLEC family like 1
VGNC:53982
100687100
Horse
SIGLEC family like 1 [Source:HGNC Symbol;Acc:HGNC:26856]
Cow
SIGLEC family like 1 [Source:HGNC Symbol;Acc:HGNC:26856]
Species
Name
OMA
EggNOG
Inparanoid
Dog
SIGLEC family like 1
Horse
SIGLEC family like 1 [Source:HGNC Symbol;Acc:HGNC:26856]
Cow
SIGLEC family like 1 [Source:HGNC Symbol;Acc:HGNC:26856]
Publication Statistics
PubTator Score 2.00
PubTator score by year
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Related Publications
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PMID
Year
Title