Tdark SIGLEC16 Sialic acid-binding Ig-like lectin 16

Protein Summary

Description

Putative adhesion molecule that mediates sialic-acid dependent binding to cells.

Uniprot Accession IDs

• A6NMB1
• Siglec-16

Gene Name

• SIGLEC16

Symbol

• SIGLECP16
• SIGLECP16
• Siglec-P16

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.57
cell line	0.48
tissue	0.38
biological term	0.33
cell type or tissue	0.31

Protein Classes

PANTHER Classes

Protein / Structural Protein / Myelin Protein / Sialic Acid-binding Ig-like Lectin 16

Protein / Signaling Molecule / Membrane-bound Signaling Molecule / Sialic Acid-binding Ig-like Lectin 16

Protein / Receptor / Cytokine Receptor / Immunoglobulin Receptor Superfamily / Sialic Acid-binding Ig-like Lectin 16

Protein / Defense/immunity Protein / Immunoglobulin Receptor Superfamily / Sialic Acid-binding Ig-like Lectin 16

Protein / Cell Adhesion Molecule / Immunoglobulin Superfamily Cell Adhesion Molecule / Sialic Acid-binding Ig-like Lectin 16

DTO Classes

Protein / Receptor / Cytokine Receptor / Immunoglobulin Receptor Superfamily / Sialic Acid-binding Ig-like Lectin 16

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 0   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0