SHANK2
SH3 and multiple ankyrin repeat domains protein 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 0.85 | ||
protein domain | 0.85 | ||
cellular component | 0.75 | ||
disease perturbation | 0.74 | ||
transcription factor | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Neurexins and neuroligins | ||||
Reactome | Neuronal System | ||||
Reactome | Protein-protein interactions at synapses | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Neurexins and neuroligins | ||||
Neuronal System | ||||
Protein-protein interactions at synapses | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
1 | 1 | 0 | 1 | 60.5 | |||||
1 | 1 | 1 | 47.7 | ||||||
vitamin D measurement | 1 | 1 | 1 | 32.7 | |||||
1 | 1 | 0 | 1.1 | 26.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1 | 60.5 | |||||
1 | 47.7 | ||||||
vitamin D measurement | 1 | 32.7 | |||||
0 | 1.1 | 26.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | SH3 and multiple ankyrin repeat domains 2 | VGNC:13317 | 466694 | |||||
Macaque | SH3 and multiple ankyrin repeat domains 2 | 708192 | ||||||
Mouse | MGI:2671987 | 210274 | ||||||
Rat | RGD:628772 | 171093 | ||||||
Rat | RGD:9143352 | 103690160 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | SH3 and multiple ankyrin repeat domains 2 | |||||
Macaque | SH3 and multiple ankyrin repeat domains 2 | |||||
Mouse | ||||||
Rat | ||||||
Rat | ||||||
PMID | Year | Title |
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