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Tdark
SH3BP5L
SH3 domain-binding protein 5-like

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366472
  • ENSP00000355428
  • ENSG00000175137

Symbol
  • KIAA1720
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.82
cellular component
0.64
histone modification site profile
0.62
tissue sample
0.61
cell type or tissue
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.42   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.42   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (48)
BICD1
Tbio
Novelty:  0.02109123
p_int:  0.999999999
p_ni:  1e-9
Score:  0.206
Data Source:  BioPlex,STRINGDB
THG1L
Tbio
Family:  Enzyme
Novelty:  0.17339179
p_int:  0.999999387
p_ni:  6.04e-7
p_wrong:  9e-9
Score:  0.206
Data Source:  BioPlex,STRINGDB
TNKS
Tchem
Family:  Enzyme
Novelty:  0.00404545
p_int:  0.999996488
p_ni:  0.000003512
Data Source:  BioPlex
TNKS2
Tchem
Family:  Enzyme
Novelty:  0.00938509
p_int:  0.999996413
p_ni:  0.000003587
Data Source:  BioPlex
BTRC
Tbio
Novelty:  0.00293475
p_int:  0.999767494
p_ni:  0.000232506
Data Source:  BioPlex
RAB11B
Tbio
Family:  Enzyme
Novelty:  0.00557558
p_int:  0.999729836
p_ni:  0.000270135
p_wrong:  2.9e-8
Score:  0.395
Data Source:  BioPlex,STRINGDB
RAB11A
Tbio
Family:  Enzyme
Novelty:  0.00153551
p_int:  0.999547747
p_ni:  0.000452253
Score:  0.636
Data Source:  BioPlex,STRINGDB
PPP1R12A
Tbio
Family:  Enzyme
Novelty:  0.0028297
p_int:  0.999479896
p_ni:  0.000520103
p_wrong:  1e-9
Score:  0.169
Data Source:  BioPlex,STRINGDB
HEXIM1
Tbio
Novelty:  0.0142443
p_int:  0.999076129
p_ni:  0.000923871
Data Source:  BioPlex
MIPOL1
Tbio
Novelty:  0.2456
p_int:  0.998858331
p_ni:  0.000317246
p_wrong:  0.000824423
Score:  0.187
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
systolic blood pressure
1
1
1
21.1
platelet crit
1
1
1
15.5
mean corpuscular volume
1
1
1
14.1
platelet count
1
1
1
13.6
monocyte count
1
1
1
12.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
systolic blood pressure
1
21.1
platelet crit
1
15.5
mean corpuscular volume
1
14.1
platelet count
1
13.6
monocyte count
1
12.3
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SH3 binding domain protein 5 like
VGNC:8483
457884
Macaque
SH3 binding domain protein 5 like
710289
Mouse
MGI:1933124
79566
Rat
RGD:1590939
690898
Dog
SH3 binding domain protein 5 like
VGNC:46121
482700
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SH3 binding domain protein 5 like
Macaque
SH3 binding domain protein 5 like
Mouse
Rat
Dog
SH3 binding domain protein 5 like
Publication Statistics
PubMed Score 0.42
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title