SF3B1
Splicing factor 3B subunit 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 1 | ||
kinase perturbation | 0.99 | ||
transcription factor perturbation | 0.88 | ||
drug perturbation | 0.87 | ||
protein complex | 0.87 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | B-WICH complex positively regulates rRNA expression | ||||
Reactome | Epigenetic regulation of gene expression | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Metabolism of RNA | ||||
Reactome | Positive epigenetic regulation of rRNA expression | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
B-WICH complex positively regulates rRNA expression | ||||
Epigenetic regulation of gene expression | ||||
Gene expression (Transcription) | ||||
Metabolism of RNA | ||||
Positive epigenetic regulation of rRNA expression | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
chronotype measurement | 1 | 2 | 0 | 1 | 76.1 | ||||
8 | 5 | 2 | 1.1 | 75.7 | |||||
Eczema | 1 | 1 | 0 | 1 | 57.3 | ||||
1 | 1 | 0 | 1 | 57.3 | |||||
1 | 2 | 0 | 1.1 | 52 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
chronotype measurement | 0 | 1 | 76.1 | ||||
2 | 1.1 | 75.7 | |||||
Eczema | 0 | 1 | 57.3 | ||||
0 | 1 | 57.3 | |||||
0 | 1.1 | 52 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | splicing factor 3b subunit 1 | VGNC:2814 | 459850 | |||||
Macaque | splicing factor 3b subunit 1 | 697773 | ||||||
Mouse | MGI:1932339 | 81898 | ||||||
Rat | RGD:620148 | 84486 | ||||||
Dog | splicing factor 3b subunit 1 | VGNC:46069 | 488456 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | splicing factor 3b subunit 1 | |||||
Macaque | splicing factor 3b subunit 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | splicing factor 3b subunit 1 | |||||
PMID | Year | Title |
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