You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
SERPINB2
Plasminogen activator inhibitor 2

Protein Summary
Description
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000299502
  • ENSP00000299502
  • ENSG00000197632
  • ENST00000457692
  • ENSP00000401645

Symbol
  • PAI2
  • PLANH2
  • PAI
  • PAI2
  • PAI-2
  • PLANH2
  • HsT1201
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
1
disease
0.78
small molecule perturbation
0.76
virus perturbation
0.72
interacting protein
0.7


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 574.43   (req: < 5)
Gene RIFs: 65   (req: <= 3)
Antibodies: 419   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 574.43   (req: >= 5)
Gene RIFs: 65   (req: > 3)
Antibodies: 419   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0