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Tbio
SERPINA9
Serpin A9

Protein Summary
Description
Protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000298845
  • ENSP00000298845
  • ENSG00000170054
  • ENST00000337425
  • ENSP00000337133
  • ENST00000380365
  • ENSP00000369723
  • ENST00000424550
  • ENSP00000409012
  • ENST00000448305
  • ENSP00000414092
  • ENST00000538527
  • ENSP00000441511
  • ENST00000546329
  • ENSP00000445476

Symbol
  • GCET1
  • SERPINA11
  • GCET1
  • SERPINA11
  • SERPINA11b
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.85
cell line
0.59
cell type or tissue
0.46
protein domain
0.41
phenotype
0.4


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.88   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 149   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.88   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 149   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0