You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
SERPINA12
Serpin A12

Protein Summary
Description
Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000341228
  • ENSP00000342109
  • ENSG00000165953
  • ENST00000556881
  • ENSP00000451738

Symbol
  • OL-64
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.78
biological term
0.68
biological process
0.54
cell line
0.53
protein complex
0.48


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 266.85   (req: < 5)
Gene RIFs: 110   (req: <= 3)
Antibodies: 336   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 266.85   (req: >= 5)
Gene RIFs: 110   (req: > 3)
Antibodies: 336   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0