Protein Summary
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). SEPT14 is a member of the highly conserved septin family of GTP-binding cytoskeletal proteins implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis, and other cellular functions (Peterson et al., 2007 [PubMed 17922164]).[supplied by OMIM, Jul 2008]
- ENST00000388975
- ENSP00000373627
- ENSG00000154997
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.76 | ||
interacting protein | 0.71 | ||
microRNA | 0.59 | ||
cell type or tissue | 0.52 | ||
tissue | 0.48 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 18.44 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 85 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 18.44 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 85 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0