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Tdark
SEL1L3
Protein sel-1 homolog 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000264868
  • ENSP00000264868
  • ENSG00000091490
  • ENST00000399878
  • ENSP00000382767
  • ENST00000502949
  • ENSP00000425438

Symbol
  • KIAA0746
  • Sel-1L3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.97
PubMedID
0.95
gene perturbation
0.91
disease perturbation
0.79
virus perturbation
0.76


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.88   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 70   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.88   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (43)
SCGB1D1
Tbio
Novelty:  0.04199997
p_int:  0.998653292
p_ni:  0.001346644
p_wrong:  6.4e-8
Score:  0.195
Data Source:  BioPlex,STRINGDB
LAMP3
Tbio
Novelty:  0.01677383
p_int:  0.998426906
p_ni:  0.001573091
p_wrong:  3e-9
Data Source:  BioPlex
PLTP
Tbio
Novelty:  0.00267612
p_int:  0.998151205
p_ni:  0.001848795
Score:  0.768
Data Source:  BioPlex,STRINGDB
RLN1
Tbio
Novelty:  0.03992636
p_int:  0.997440549
p_ni:  0.002552513
p_wrong:  0.000006938
Data Source:  BioPlex
MINDY1
Tbio
Novelty:  0.31540765
p_int:  0.993089654
p_ni:  0.002775361
p_wrong:  0.004134985
Score:  0.19
Data Source:  BioPlex,STRINGDB
OS9
Tbio
Novelty:  0.01490339
Score:  0.675
Data Source:  STRINGDB
ERLEC1
Tbio
Novelty:  0.01243855
Score:  0.675
Data Source:  STRINGDB
LRGUK
Tdark
Family:  Enzyme
Novelty:  0.42433819
Score:  0.654
Data Source:  STRINGDB
KRBA1
Tdark
Novelty:  2.59384945
Score:  0.65
Data Source:  STRINGDB
AZIN1
Tbio
Family:  Enzyme
Novelty:  0.03017595
Score:  0.605
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
systolic blood pressure change measurement
1
1
0
49
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
systolic blood pressure change measurement
0
49
17.8
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SEL1L family member 3
VGNC:7056
461150
Macaque
SEL1L family member 3
695033
Mouse
MGI:1916941
231238
Rat
RGD:1562860
360945
Dog
SEL1L family member 3
VGNC:53240
488849
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SEL1L family member 3
Macaque
SEL1L family member 3
Mouse
Rat
Dog
SEL1L family member 3
Publication Statistics
PubMed Score 1.88
PubMed score by year
PubTator Score 0.08
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title