SDHC
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 1 | ||
transcription factor perturbation | 0.97 | ||
cellular component | 0.91 | ||
transcription factor binding site profile | 0.84 | ||
co-expressed gene | 0.76 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Citric acid cycle (TCA cycle) | ||||
Reactome | Metabolism | ||||
Reactome | Pyruvate metabolism and Citric Acid (TCA) cycle | ||||
Reactome | Respiratory electron transport | ||||
Reactome | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Citric acid cycle (TCA cycle) | ||||
Metabolism | ||||
Pyruvate metabolism and Citric Acid (TCA) cycle | ||||
Respiratory electron transport | ||||
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
serum non-albumin protein measurement | 1 | 4 | 4 | 93.4 | |||||
blood protein measurement | 1 | 4 | 4 | 93.2 | |||||
mean platelet volume | 3 | 2 | 4 | 93 | |||||
blood metabolite measurement | 2 | 2 | 2 | 83 | |||||
4 | 2 | 0 | 1.1 | 82.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
serum non-albumin protein measurement | 4 | 93.4 | |||||
blood protein measurement | 4 | 93.2 | |||||
mean platelet volume | 4 | 93 | |||||
blood metabolite measurement | 2 | 83 | |||||
0 | 1.1 | 82.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | succinate dehydrogenase complex subunit C | 719978 | ||||||
Mouse | MGI:1913302 | 66052 | ||||||
Rat | RGD:1359454 | 289217 | ||||||
Dog | succinate dehydrogenase complex subunit C | VGNC:45952 | 478983 | |||||
Horse | succinate dehydrogenase complex subunit C | VGNC:22774 | 100065940 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | succinate dehydrogenase complex subunit C | |||||
Mouse | ||||||
Rat | ||||||
Dog | succinate dehydrogenase complex subunit C | |||||
Horse | succinate dehydrogenase complex subunit C | |||||
PMID | Year | Title |
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