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Tdark
SDAD1
Protein SDA1 homolog

Protein Summary
Description
Required for 60S pre-ribosomal subunits export to the cytoplasm.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000356260
  • ENSP00000348596
  • ENSG00000198301

Symbol
  • NUC130
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
0.83
interacting protein
0.8
transcription factor binding site profile
0.76
transcription factor perturbation
0.74
tissue sample
0.73


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.45   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 37   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.45   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 37   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (362)
RPL36AL
Tbio
Novelty:  0.09336423
p_int:  0.999893983
p_ni:  0.000106017
Data Source:  BioPlex
RPL36A
Tbio
Novelty:  0.06115838
p_int:  0.99939509
p_ni:  0.00060491
Data Source:  BioPlex
RBM34
Tdark
Novelty:  0.58131282
p_int:  0.998287655
p_ni:  0.001712345
Score:  0.882
Data Source:  BioPlex,STRINGDB
NAP1L1
Tbio
Novelty:  0.03895314
p_int:  0.988296041
p_ni:  0.011703959
Score:  0.751
Data Source:  BioPlex,STRINGDB
MAGEB10
Tdark
Novelty:  2.96156972
p_int:  0.982467054
p_ni:  0.017532946
Data Source:  BioPlex
RPS14
Tbio
Novelty:  0.00576737
p_int:  0.981053572
p_ni:  0.018946428
Score:  0.239
Data Source:  BioPlex,STRINGDB
CDX1
Tbio
Family:  TF
Novelty:  0.00815821
p_int:  0.910595671
p_ni:  0.089404329
Data Source:  BioPlex
RPL18A
Tbio
Novelty:  0.04612948
p_int:  0.850934248
p_ni:  0.149065751
Score:  0.544
Data Source:  BioPlex,STRINGDB
ZBTB38
Tbio
Family:  TF
Novelty:  0.05048192
p_int:  0.816942453
p_ni:  0.183057546
p_wrong:  1e-9
Score:  0.186
Data Source:  BioPlex,STRINGDB
FGF8
Tbio
Novelty:  0.00155113
p_int:  0.815114195
p_ni:  0.184885805
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
HPA
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
C-X-C motif chemokine 10 measurement
2
2
0
1.7
91.4
fetal genotype effect measurement
1
1
1
61.4
protein measurement
1
1
1
61.4
monokine induced by gamma interferon measurement
1
2
2
57.7
waist circumference
1
1
1
2.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
C-X-C motif chemokine 10 measurement
0
1.7
91.4
fetal genotype effect measurement
1
61.4
protein measurement
1
61.4
monokine induced by gamma interferon measurement
2
57.7
waist circumference
1
2.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (16)
1 – 5 of 16
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SDA1 domain containing 1
VGNC:679
471201
Macaque
SDA1 domain containing 1
700863
Mouse
MGI:2140779
231452
Rat
RGD:1359112
289504
Dog
SDA1 domain containing 1
VGNC:45941
478431
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SDA1 domain containing 1
Macaque
SDA1 domain containing 1
Mouse
Rat
Dog
SDA1 domain containing 1
Publication Statistics
PubMed Score 4.45
PubMed score by year
PubTator Score 2.08
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title