Tbio SDAD1 Protein SDA1 homolog

Protein Summary

Description

Required for 60S pre-ribosomal subunits export to the cytoplasm.

Uniprot Accession IDs

• Q9NVU7
• Q32Q11
• Q68D52
• Q7Z5U4
• Q9H831
• Q9H9P6

Gene Name

• SDAD1

Ensembl ID

• ENST00000356260
• ENSP00000348596
• ENSG00000198301

Symbol

• NUC130

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
ligand (protein) perturbation	0.83
interacting protein	0.8
transcription factor binding site profile	0.76
transcription factor perturbation	0.74
tissue sample	0.73

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.57   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 37   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.57   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 37   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0