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Tbio
SCPEP1
Retinoid-inducible serine carboxypeptidase

Protein Summary
Description
May be involved in vascular wall and kidney homeostasis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000262288
  • ENSP00000262288
  • ENSG00000121064
  • ENST00000576154
  • ENSP00000458587

Symbol
  • RISC
  • SCP1
  • RISC
  • HSCP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.96
disease perturbation
0.95
histone modification site profile
0.88
transcription factor perturbation
0.88
small molecule perturbation
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.22   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 100   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.22   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
FURIN
Tchem
Family:  Enzyme
Novelty:  0.00055079
p_int:  0.999949502
p_ni:  0.000050493
p_wrong:  5e-9
Score:  0.179
Data Source:  BioPlex,STRINGDB
CTU1
Tbio
Novelty:  0.04670058
p_int:  0.999925911
p_ni:  0.000074089
Data Source:  BioPlex
GALNT16
Tbio
Family:  Enzyme
Novelty:  0.34686672
p_int:  0.999923622
p_ni:  0.000003586
p_wrong:  0.000072791
Data Source:  BioPlex
C15orf39
Tdark
Novelty:  1.68615093
p_int:  0.998470597
p_ni:  0.001528181
p_wrong:  0.000001222
Data Source:  BioPlex
SELENOT
Tbio
Novelty:  0.02480242
p_int:  0.997921491
p_ni:  0.002077059
p_wrong:  0.00000145
Data Source:  BioPlex
GMCL1
Tbio
Novelty:  0.1543762
p_int:  0.995447652
p_ni:  0.00321631
p_wrong:  0.001336038
Data Source:  BioPlex
CTU2
Tdark
Novelty:  0.00936441
p_int:  0.992985705
p_ni:  0.007014294
p_wrong:  1e-9
Data Source:  BioPlex
STAP1
Tbio
Novelty:  0.17498048
p_int:  0.955047382
p_ni:  9.9e-8
p_wrong:  0.044952519
Data Source:  BioPlex
CADM4
Tbio
Novelty:  0.05034541
p_int:  0.939923893
p_ni:  0.043357731
p_wrong:  0.016718376
Data Source:  BioPlex
ITIH2
Tbio
Novelty:  0.04886358
p_int:  0.933140913
p_ni:  0.047017493
p_wrong:  0.019841594
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
serine carboxypeptidase 1
VGNC:12668
455148
Mouse
MGI:1921867
74617
Rat
RGD:620067
114861
Dog
serine carboxypeptidase 1 [Source:HGNC Symbol;Acc:HGNC:29507]
Horse
serine carboxypeptidase 1
VGNC:22749
100070731
Species
Name
OMA
EggNOG
Inparanoid
Chimp
serine carboxypeptidase 1
Mouse
Rat
Dog
serine carboxypeptidase 1 [Source:HGNC Symbol;Acc:HGNC:29507]
Horse
serine carboxypeptidase 1
Publication Statistics
PubMed Score 12.22
PubMed score by year
PubTator Score 263.11
PubTator score by year
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Related Publications
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PMID
Year
Title